Patologia Clínica, Universidade Federal do Triângulo Mineiro, Uberaba, MG, Brazil.
J Pediatr (Rio J). 2011 Sep-Oct;87(5):457-60. doi: 10.2223/JPED.2104. Epub 2011 Jul 21.
To compare serum retinol levels in preschool children during an episode of pneumonia and 45 days after the resolution of the infection.
The study was conducted with preschool children without any infection (control group, n = 9) or children hospitalized for pneumonia (n = 12), who were evaluated soon after hospitalization (phase 1) and 45 days later (phase 2). Nutritional assessment included anthropometric measurements, a food questionnaire, and laboratory blood routine examination, including urinary and serum retinol levels. Paired Student t or Mann-Whitney tests were used as required.
Food intake was similar between groups. Blood hemoglobin and serum sodium and albumin decreased during phase 1, while there were higher C-reactive protein serum values. Urinary retinol levels remained unchanged whereas serum retinol increased significantly after pneumonia recovery.
During the course of pneumonia, children had transient decrease in serum levels of vitamin A, an epiphenomenon of the acute phase response.
比较肺炎发作期间和感染消退后 45 天学龄前儿童的血清视黄醇水平。
本研究纳入了无感染的学龄前儿童（对照组，n=9）或因肺炎住院的儿童（n=12），他们在住院后不久（第 1 阶段）和 45 天后（第 2 阶段）进行评估。营养评估包括人体测量、食物问卷和实验室血常规检查，包括尿和血清视黄醇水平。根据需要使用配对学生 t 检验或曼-惠特尼检验。
两组的食物摄入量相似。第 1 阶段时，血血红蛋白和血清钠、白蛋白降低，而 C 反应蛋白血清值升高。尿视黄醇水平保持不变，而肺炎恢复后血清视黄醇显著增加。
在肺炎病程中，儿童的血清维生素 A 水平会出现短暂下降，这是急性期反应的一个表现。
