Mendes Marcio Henrique, Sakata Lisandro, Betinjane Alberto Jorge
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, SP, Brasil.
Arq Bras Oftalmol. 2011 Mar-Apr;74(2):85-7. doi: 10.1590/s0004-27492011000200002.
To study the distribution of the central corneal thickness and its correlations with other biometric data in patients with congenital glaucoma.
Patients had been divided into two groups: group "A", composed of patients with congenital glaucoma, being subdivided in two sub-groups: with Haab striae (A1) and without Haab striae (A2), and group"B" that represented the controls.
The group A presented corneal diameter between 11 and 15.5 mm, with mean of 14.13 mm and standard deviation (SD) of 1.28, while group B presented values between 11.5 and 12.5 mm, with average of 12.01 mm SD of 0.09 (t=-8.9723 and p=1.5083 in level 0.05). Glaucomatous patients presented greater mean values of axial diameter (t=-6.46315, p=9.2498 with level of significance of 0.05), and smaller mean keratometry in relation to the controls. The A1 sub-group presented mean central corneal thickness of 539 ± 46 µm, the A2 presented 571 ± 56 µm, and Group B 559 ± 28 µm (t=0.43746 and p=0.66291). The correlation between corneal and axial diameters was positive in both groups. The correlation between corneal diameter and mean keratometric values was negative in both groups.
Patients with congenital glaucoma presented greater mean of axial dia meter and smaller mean keratometric values compared to the controls. No statistical significant difference of the central corneal thickness was demonstrated. Corneal and axial diameters were correlated positively. Corneal diameter was correlated negatively with the mean keratometry. It was not possible to establish correlations between the central corneal thickness and other biometric data.
研究先天性青光眼患者中央角膜厚度的分布及其与其他生物测量数据的相关性。
患者被分为两组：“A组”，由先天性青光眼患者组成，再细分为两个亚组：有哈布条纹的（A1）和无哈布条纹的（A2），以及代表对照组的“B组”。
A组角膜直径在11至15.5毫米之间，平均值为14.13毫米，标准差（SD）为1.28，而B组的值在11.5至12.5毫米之间，平均值为12.01毫米，SD为0.09（在0.05水平时t=-8.9723，p=1.5083）。青光眼患者的眼轴直径平均值更大（在显著性水平为0.05时t=-6.46315，p=9.2498），与对照组相比角膜曲率计平均值更小。A1亚组中央角膜厚度平均值为539±46微米，A2组为571±56微米，B组为559±28微米（t=0.43746，p=0.66291）。两组中角膜直径与眼轴直径之间的相关性均为正。两组中角膜直径与平均角膜曲率值之间的相关性均为负。
与对照组相比，先天性青光眼患者的眼轴直径平均值更大，角膜曲率计平均值更小。未显示中央角膜厚度有统计学显著差异。角膜直径与眼轴直径呈正相关。角膜直径与平均角膜曲率呈负相关。无法在中央角膜厚度与其他生物测量数据之间建立相关性。
