Laboratório de Hantaviroses e Rickettsioses, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brasil.
Rev Soc Bras Med Trop. 2011 May-Jun;44(3):395-6. doi: 10.1590/s0037-86822011000300028.
Brazilian spotted fever (BSF) is the most important and frequent rickettsial disease in Brazil. A fatal case of BSF is reported in a 32-year-old black man, who died of irreversible shock after five days of fever, severe headache and abdominal pain with no rash. Spleen, kidney and heart samples collected at autopsy were positive for Rickettsia rickettsii by PCR and sequencing. The authors emphasize the need for a high index of diagnostic suspicion for spotted fever in black patients. Absence of a skin rash should not dissuade clinicians from considering the possibility of BSF and initiating empirical therapy.
巴西出血热（BSF）是巴西最重要和最常见的立克次体病。报告了一例致命的 BSF 病例，患者为 32 岁黑人男性，发热 5 天后死于不可逆性休克，伴有严重头痛和腹痛，无皮疹。尸检采集的脾、肾和心样本通过 PCR 和测序均为立氏立克次体阳性。作者强调，对黑人患者的斑疹热需要高度的诊断怀疑指数。无皮疹不应阻止临床医生考虑 BSF 的可能性并开始经验性治疗。
