Geleneky Markéta
Clinic of Infectious Diseases, University Hospital Bulovka Prague, Czech Republic.
Klin Mikrobiol Infekc Lek. 2011 Jun;17(3):96-9.
In common practice, toxoplasmosis may be a source of frequent diagnostic and therapeutic dilemmas. Three case reports are presented, illustrating the most frequent 'non-standard" situations resulting in erroneous interpretation of findings and therapeutic decisions. The first case was false or non-specific positivity of antibodies of several classes, leading to a heavy mental burden and wrong prenatal therapy in a pregnant patient. In the second case, persistent low IgG avidity was not interpreted in the context of other results, leading to a hasty decision to terminate the pregnancy. The third case report describes a wrong combination of therapy resulting in the development of numerous adverse effects in a young patient with repeated abortions.
在临床实践中,弓形虫病可能是频繁导致诊断和治疗困境的一个原因。本文介绍了三例病例报告,阐述了最常见的“非标准”情况,这些情况会导致对检查结果的错误解读和治疗决策失误。第一例病例中,几类抗体出现假阳性或非特异性阳性,给一名孕妇带来了沉重的精神负担并导致了错误的产前治疗。第二例病例中,持续的低IgG亲和力未结合其他检查结果进行解读,导致仓促做出终止妊娠的决定。第三例病例报告描述了一名有反复流产史的年轻患者因错误的联合治疗引发了诸多不良反应。