[孕前及孕期1307名妇女血清中TORCH特异性IgM和IgG的检测]

[Detection the serum IgM and IgG specific for TORCH in 1307 women in the period of pre-pregnancy and pregnancy].

作者信息

Qin Wen, Hu Da-chun, Pang Hai-li

机构信息

Department of Clinical Laboratory, First People's Hospital of Kunming, China.

出版信息

Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2011 Aug;25(4):292-4.

PMID:22097611

Abstract

OBJECTIVE

The objective is to obtain the information of women in the period of prepregnancy and pregnancy infected by TORCH (Toxoplasma, Rabella Virus, Cytomegalovirus, and Herpes Simplex Virus) in Kunming for preventing fetus from infection by TORCH in uterus.

METHODS

The serum IgM and IgG specific for TORCH from 1307 women in the period of pre-pregnancy and pregnancy were measured with ELISA and The reagent is the product of virion/serion.

RESULTS

The serum IgM specific for TORCH were detected in 2.83% of 1307 pregnant women for Toxoplasma, 2.37% for Rebulla Virus, 0.46% for Cytomegalovirus, 2.45% for Herpes Simplex Virus. The total positive rate of serum IgM specific for TORCH was 1.45%. The serum IgG specific for TORCH were detected in 3.98% of 1307 pregnant women for Toxoplasma, 72.3% for Rebulla Virus, 97.78% for Cytomegalovirus, 80.34% for Herpes Simplex Virus. The total positive rate of serum IgG specific for TORCH was 63.60%. There was no significant difference among the women with different pregnant situation in terms of the serum IgM and IgG specific for TORCH.

CONCLUSION

There are some of women in the period of pre-pregnancy and pregnancy with current infection by TORCH in Kunming. It is recommended to screen for infection by TORCH in women in the period of pre-pregnancy and pregnancy to prevent fetus from infection by TORCH in uterus.

摘要

目的

了解昆明市孕前及孕期妇女感染弓形虫（Toxoplasma）、风疹病毒（Rabella Virus）、巨细胞病毒（Cytomegalovirus）和单纯疱疹病毒（Herpes Simplex Virus）（TORCH）的情况，以预防胎儿宫内感染TORCH。

方法

采用酶联免疫吸附试验（ELISA）检测1307例孕前及孕期妇女血清中TORCH特异性IgM和IgG，试剂为病毒颗粒/血清型产品。

结果

1307例孕妇中，弓形虫IgM阳性率为2.83%，风疹病毒IgM阳性率为2.37%，巨细胞病毒IgM阳性率为0.46%，单纯疱疹病毒IgM阳性率为2.45%，TORCH-IgM总阳性率为1.45%。弓形虫IgG阳性率为3.98%，风疹病毒IgG阳性率为72.3%，巨细胞病毒IgG阳性率为97.78%，单纯疱疹病毒IgG阳性率为80.34%，TORCH-IgG总阳性率为63.60%。不同妊娠情况的妇女TORCH特异性IgM和IgG阳性率差异无统计学意义。