Huang S L
Zhan-jiang Medical College.
Zhonghua Fu Chan Ke Za Zhi. 1990 Nov;25(6):337-9, 382-3.
Detection of cytomegaloviruses (CMV) DNA in urine samples from pregnant women and newborns' cord blood was done by DNA-DNA hybridization. 33.3% of pregnant women showed CMV DNA sequences in the 1-3 months, 36.4% in the 4-6 months and 38.2% in the 7-9 months. The results suggested that the CMV infection rate of pregnant women increased as time went on.75.0% women with history of abnormal pregnancies showed CMV in their urine and 30.4% newborns' cord blood was positive for CMV. It is apparently that CMV infection rate in women with history of abnormal pregnancies was much higher than that of normal pregnant women and the danger of miscarriage in pregnant women with primary CMV infection at early pregnancy increased. CMV congenital infection rate was also high in newborns.
采用DNA-DNA杂交技术检测孕妇尿液样本及新生儿脐带血中的巨细胞病毒(CMV)DNA。1 - 3个月的孕妇中33.3%检测出CMV DNA序列,4 - 6个月的孕妇中这一比例为36.4%,7 - 9个月的孕妇中为38.2%。结果表明,孕妇的CMV感染率随时间推移而上升。有异常妊娠史的孕妇中75.0%尿液检测出CMV,新生儿脐带血中30.4% CMV呈阳性。显然,有异常妊娠史的女性CMV感染率远高于正常孕妇,孕早期原发性CMV感染的孕妇流产风险增加。新生儿的CMV先天性感染率也很高。