Department of Complementary & Alternative Medicine, John A Burns School of Medicine, University of Hawaii at Manoa, 651 Ilalo Street, Honolulu, HI 96813, USA.
Expert Rev Gastroenterol Hepatol. 2011 Aug;5(4):465-77. doi: 10.1586/egh.11.46.
A large number of autoimmune disorders have a gastrointestinal (GI) dysfunction component that may interplay with genetic, hormonal, environmental and/or stress factors. This narrarive review investigates possible links between autism, immune system abnormalities and GI symptoms in a subgroup of children with autism. A literature search on Medline (1950 to September 2010) was conducted to identify relevant articles by using the keywords 'autism and gastrointestinal' (71 publications) and 'autism and immune' (237 publications), cross-referencing and general searching to evaluate the available literature on the immunological and GI aspects of autism. Sufficient evidence exists to support that a subgroup of children with autism may suffer from concomitant immune-related GI symptoms.
许多自身免疫性疾病都存在胃肠道（GI）功能障碍的成分，这可能与遗传、激素、环境和/或压力因素相互作用。本综述研究了自闭症患儿亚群中自闭症、免疫系统异常和胃肠道症状之间的可能联系。通过使用关键词“自闭症和胃肠道”（71 篇文章）和“自闭症和免疫”（237 篇文章）在 Medline（1950 年至 2010 年 9 月）上进行文献检索，并交叉参考和全面搜索，以评估关于自闭症免疫和胃肠道方面的现有文献。有足够的证据表明，自闭症患儿亚群可能同时患有与免疫相关的胃肠道症状。
