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从卵巢甲状腺肿到桥本甲状腺炎——原发性甲状腺功能减退症的不常见诊断:病例报告。

From struma ovarii to Hashimoto disease--an unusual diagnosis of primary hypothyroidism: case report.

机构信息

Department of Endocrinology and Internal Medicine, Medical University in Gdansk, Poland.

出版信息

Gynecol Endocrinol. 2012 Jan;28(1):43-5. doi: 10.3109/09513590.2011.588750. Epub 2011 Jul 23.

DOI:10.3109/09513590.2011.588750
PMID:21780949
Abstract

CAPSULE

Authors report a case of a 52-year-old woman after struma ovarii with chronic lymphocytic inflammation excision. Finally thyroxin treatment was started and patient's hypothyroidism symptoms diminished.

CASE SUMMARY

Struma ovarii is a type of mature teratoma in which thyroid tissue forms the main component. In most cases struma ovarii is composed of normal thyroid tissue while lymphocytic thyroiditis in struma ovarii occurs very rarely. The authors report a case of a 52-year-old woman after ovarian tumor excision. In histopatholgical examination struma ovarii with chronic lymphocytic inflammation was diagnosed. Additional studies revealed a typical ultrasonographic picture of Hashimoto disease in the thyroid gland and an increased concentration of thyroglobulin antibodies. A final diagnosis of Hashimoto disease was confirmed. Initially, thyroid gland function was normal but 11 months after surgery, supplementation therapy with thyroxin was administered. In this case, an early diagnosis of Hashimoto disease resulted from excision of struma ovarii with chronic lymphocytic inflammation. It induced early thyroxin treatment and allowed to reduce hypothyroidism symptoms.

摘要

文摘

作者报告了一例 52 岁女性,在卵巢肿瘤切除术后患有慢性淋巴细胞性甲状腺炎的甲状腺滤泡性腺瘤。最终开始了甲状腺素治疗,患者的甲状腺功能减退症状减轻。

病例总结

甲状腺滤泡性腺瘤是一种成熟的畸胎瘤,其中甲状腺组织是主要成分。在大多数情况下,甲状腺滤泡性腺瘤由正常的甲状腺组织组成,而甲状腺滤泡性腺瘤中的淋巴细胞性甲状腺炎非常罕见。作者报告了一例 52 岁女性,在卵巢肿瘤切除术后患有慢性淋巴细胞性甲状腺炎的甲状腺滤泡性腺瘤。在组织病理学检查中诊断为甲状腺滤泡性腺瘤伴慢性淋巴细胞性甲状腺炎。进一步研究显示甲状腺有桥本甲状腺炎的典型超声图像,且甲状腺球蛋白抗体浓度升高。最终诊断为桥本甲状腺炎。最初,甲状腺功能正常,但在手术后 11 个月,给予甲状腺素补充治疗。在这种情况下,由于切除慢性淋巴细胞性甲状腺炎的甲状腺滤泡性腺瘤,早期诊断为桥本甲状腺炎。这导致了早期甲状腺素治疗,并允许减少甲状腺功能减退症状。

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