Dogra S, Suri D, Saini A G, Rawat A, Sodhi K S
Department of Pediatrics, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Ann Trop Paediatr. 2011;31(3):259-61. doi: 10.1179/1465328111Y.0000000019.
Nimesulide is a frequently used non-steroidal anti-inflammatory drug with analgesic and antipyretic effects in children. In view of fatal adverse drug reactions, however, its safety has been questioned. A 5-year-old boy developed Stevens-Johnson syndrome following use of nimesulide which was later complicated by rapidly progressive fatal bronchiolitis obliterans.
尼美舒利是一种常用于儿童的具有镇痛和解热作用的非甾体抗炎药。然而,鉴于其致命的药物不良反应,其安全性受到了质疑。一名5岁男孩在使用尼美舒利后出现了史蒂文斯-约翰逊综合征,随后并发了快速进展的致命性闭塞性细支气管炎。