Lin Zhong-qiu, Xie Zhi-quan, Wang Yin-ling, Qian Yun-feng, Wu Zi-qiang, Pan Chun-mei, Wang Xiao-hui
Geriatric Department of General Hospital of Guangzhou Military Command of PLA, Guangzhou 510010, China.
Zhonghua Xin Xue Guan Bing Za Zhi. 2011 May;39(5):457-62.
To determine the prevalence and clinical characteristics of orthostatic hypotension (OH) in the elderly and retired population.
A total of 1174 elderly and retired people underwent health screening physical examination in Guangzhou military region were included. The orthostatic blood pressure and heart rate were measured in supine position after resting for more than 5 minutes and at 0 and 2 min after standing. Subjects were divided into OH positive group and OH negative group. Orthostatic hypotension was defined as 20 mm Hg (1 mm Hg = 0.133 kPa) or greater decrease in SBP and/or 10 mm Hg or greater decrease in DBP after standing.
The prevalence of OH in this cohort was 25.6% at either 0 or 2 min after standing (21.6% or 20.7% respectively). Incidence of hypertension, myocardial infarction (MI), heart failure (HF), ischemic stroke and diabetes was significantly higher in OH positive group than in OH negative group (all P < 0.05), however, antihypertensive medication was similar between the two groups.
Orthostatic hypotension is common in the elderly and retired population and is associated with increased risk of hypertension, diabetes mellitus and cardiovascular disease.
确定老年及退休人群中体位性低血压(OH)的患病率及临床特征。
纳入广州军区1174名接受健康筛查体检的老年及退休人员。在静息5分钟以上后的仰卧位以及站立后0分钟和2分钟时测量体位性血压和心率。受试者分为OH阳性组和OH阴性组。体位性低血压定义为站立后收缩压下降20 mmHg(1 mmHg = 0.133 kPa)及以上和/或舒张压下降10 mmHg及以上。
该队列中站立后0分钟或2分钟时OH的患病率为25.6%(分别为21.6%或20.7%)。OH阳性组高血压、心肌梗死(MI)、心力衰竭(HF)、缺血性卒中和糖尿病的发生率显著高于OH阴性组(均P < 0.05),然而,两组间抗高血压药物治疗情况相似。
体位性低血压在老年及退休人群中常见,且与高血压、糖尿病和心血管疾病风险增加相关。