Accurso A, Donofrio V, Insabato L, Mosella G
Seconda Facoltà di Medicina e Chirurgia, VI Divisione di Chirurgia Generale, Università degli Studi di Napoli, Italy.
Tumori. 1990 Dec 31;76(6):606-10. doi: 10.1177/030089169007600621.
Adenomyoepithelioma is a proliferative disorder of both epithelial and myoepithelial cells. This lesion may be found in salivary glands, skin appendages and, very rarely, in the mammary gland. Adenomyoepithelioma was first described in 1970 and very few cases have so far been reviewed in the literature. This paper reports the clinical, histological and immunohistochemical characteristics of an adenomyoepithelioma in a 24 year old woman; to our knowledge this is the first published case in such a young patient. The clinical feature suggested a fibroadenoma. A more complete study of the excised tumor tissue by immunohistochemical and ultrastructural analysis proved that the correct diagnosis was adenomyoepithelioma. Whether adenomyoepithelioma is a benign or a low-grade malignant lesion is still controversial and, therefore, the therapeutic approach is not well defined.
腺肌上皮瘤是一种上皮细胞和肌上皮细胞的增殖性疾病。这种病变可见于唾液腺、皮肤附属器，极少见于乳腺。腺肌上皮瘤于1970年首次被描述，迄今为止文献中仅有少数病例报道。本文报告了一名24岁女性腺肌上皮瘤的临床、组织学及免疫组化特征；据我们所知，这是该年龄段患者中首例发表的病例。临床特征提示为纤维腺瘤。通过免疫组化和超微结构分析对切除的肿瘤组织进行更全面的研究后证实，正确诊断为腺肌上皮瘤。腺肌上皮瘤是良性还是低度恶性病变仍存在争议，因此，治疗方法尚不明确。
