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乳腺良性腺肌上皮瘤:两例罕见病例报告及文献复习

Benign adenomyoepitelioma of the breast: Presentation of two rare cases and review of literature.

作者信息

Intagliata Eva, Gangi Santi, Trovato Claudio, Vecchio Rosario, Strazzanti Angela

机构信息

Department of General Surgery and Medical Surgical Specialties, University of Catania, Policlinico Vittorio Emanuele Hospital, Via S. Sofia 78, 95123 Catania, Italy.

Department of General Surgery and Medical Surgical Specialties, University of Catania, Policlinico Vittorio Emanuele Hospital, Via S. Sofia 78, 95123 Catania, Italy.

出版信息

Int J Surg Case Rep. 2020;67:1-4. doi: 10.1016/j.ijscr.2020.01.010. Epub 2020 Jan 23.

DOI:10.1016/j.ijscr.2020.01.010
PMID:31991375
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6992528/
Abstract

INTRODUCTION

Adenomyoepithelioma of the breast is a rare benign breast neoplasm with a particular behaviour.

PRESENTATION OF CASES

We report two cases of adenomyoepithelioma of the breast in two old female patients, diagnosed over a period of 5 years. The clinical presentation, the radiological and the histopathologic findings are discussed.

DISCUSSION

Adenomyoepithelioma of the breast is characterized by the proliferation of both epithelial and myoepithelial cells belonging to the breast lobules and ducts. The imaging features are not pathognomonic and FNAB is usually not diagnostic. The morphologic appearance of this tumor varies, and it has to be considered in the differential diagnosis with other breast tumors. Although benign, adenomyoepithelioma has a potential for local recurrence, and malignant transformation is possible; therefore, wide excision is recommended to lower the recurrence rate.

CONCLUSION

The rarity of this histological type and the finding of two cases in a relatively short period makes this case report unique.

摘要

引言

乳腺腺肌上皮瘤是一种具有特殊行为的罕见乳腺良性肿瘤。

病例介绍

我们报告了两名老年女性患者的乳腺腺肌上皮瘤病例,这两例病例是在5年期间诊断出来的。文中讨论了临床表现、放射学和组织病理学发现。

讨论

乳腺腺肌上皮瘤的特征是乳腺小叶和导管的上皮细胞和肌上皮细胞均增生。其影像学特征不具有特异性,细针穿刺抽吸活检(FNAB)通常无法确诊。该肿瘤的形态外观各异,在与其他乳腺肿瘤的鉴别诊断中必须予以考虑。尽管腺肌上皮瘤是良性的,但有局部复发的可能,也有可能发生恶性转化;因此,建议广泛切除以降低复发率。

结论

这种组织学类型的罕见性以及在相对较短时间内发现两例病例使得本病例报告具有独特性。

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The SCARE 2018 statement: Updating consensus Surgical CAse REport (SCARE) guidelines.SCARE 2018 声明:更新共识手术病例报告(SCARE)指南。
Int J Surg. 2018 Dec;60:132-136. doi: 10.1016/j.ijsu.2018.10.028. Epub 2018 Oct 18.
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Lessons From Managing the Breast Malignant Adenomyoepithelioma and the Discussion on Treatment Strategy.乳腺恶性腺肌上皮瘤的管理经验及治疗策略探讨
World J Oncol. 2017 Aug;8(4):126-131. doi: 10.14740/wjon1055e. Epub 2017 Aug 27.
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Radiotherapy in the Multidisciplinary Management of Adenomyoepithelioma of the Breast with an Axillary Lymph Node Metastasis: A Case Report and Review of the Literature.伴有腋窝淋巴结转移的乳腺腺肌上皮瘤多学科管理中的放射治疗:一例报告及文献复习
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Breast adenomyoepithelioma and adenomyoepithelioma with carcinoma (malignant adenomyoepithelioma) with associated breast malignancies: A case series emphasizing histologic, radiologic, and clinical correlation.乳腺腺肌上皮瘤及伴癌的腺肌上皮瘤(恶性腺肌上皮瘤)与相关乳腺恶性肿瘤:一项强调组织学、放射学及临床相关性的病例系列研究。
Breast. 2016 Oct;29:132-9. doi: 10.1016/j.breast.2016.07.018. Epub 2016 Aug 3.
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Lobulated adenomyoepithelioma: a case report showing immunohistochemical profiles.分叶状腺肌上皮瘤:一例显示免疫组化特征的病例报告。
Int J Clin Exp Pathol. 2015 Nov 1;8(11):15407-11. eCollection 2015.
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The mammography and MRI manifestations of adenomyoepithelioma of the breast.乳腺腺肌上皮瘤的乳腺钼靶和磁共振成像表现。
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