Department of Ophthalmology, Kaohsiung Veterans General Hospital, Taiwan, ROC.
J Chin Med Assoc. 2011 Jul;74(7):310-5. doi: 10.1016/j.jcma.2011.05.007. Epub 2011 Jul 5.
To investigate the difference of ocular biometric and corneal topographic characteristics between the two eyes in high anisometropes with difference of 4 D or more in spherical component.
Fifty-one young anisometropic men were collected. Detailed ocular examinations, including cycloplegic autorefraction, best-corrected visual acuity, intraocular pressure, A-scan, and Orbscan topography were done and recorded. The comparisons between two eyes were performed and the correlations between different ocular parameters were evaluated.
The mean axial length in the more myopic/less hyperopic eye was longer than that in the less myopic/more hyperopic eye [difference 1.8 mm, 95% confidence interval (CI) 1.6-2.0 mm, p < 0.001]. The mean thinnest corneal thickness in the more myopic/less hyperopic eye was an average of 4.0 μm thicker than that in the other eye (95% CI 1.2-6.8 μm, p = 0.007). The mean anterior chamber depth in the more myopic/less hyperopic eye was an average of 0.05 mm (95% CI 0.02-0.07 mm, p < 0.001) more than that in the other eye. The curvature and size of cornea were not significantly different.
The anterior chamber depth is deeper, axial length is longer, and thinnest corneal thickness is thicker in the more myopic/less hyperopic eye of high-anisometropic patients. Anisometropic eyes provide the chance to understand the biometric changes of eyeball with different refractive statuses in the same person. Such information is helpful for us to calculate the intraocular lenses power in cataract surgery and to do the surgical planning for corneal refractive surgery in eyes of different refractive power.
研究双眼球差大于 4 屈光度的高度屈光参差患者的眼球生物测量和角膜地形特征的差异。
收集 51 例年轻的屈光参差男性患者。进行详细的眼部检查，包括睫状肌麻痹自动验光、最佳矫正视力、眼压、A 超和 Orbscan 地形图，并记录。对双眼进行比较，并评估不同眼部参数之间的相关性。
在更近视/更远视的眼中，平均眼轴长度比在较不近视/更远视的眼中长[差异 1.8mm，95%置信区间（CI）为 1.6-2.0mm，p<0.001]。在更近视/更远视的眼中，最薄角膜厚度的平均值比另一只眼厚 4.0μm[95%CI 为 1.2-6.8μm，p=0.007]。在更近视/更远视的眼中，平均前房深度比另一只眼深 0.05mm[95%CI 为 0.02-0.07mm，p<0.001]。角膜曲率和大小没有明显差异。
高度屈光参差患者的较近视/较远视眼的前房深度较深、眼轴较长、最薄角膜厚度较厚。屈光参差眼为我们提供了在同一人不同屈光状态下了解眼球生物测量变化的机会。这些信息有助于我们计算白内障手术中人工晶状体的屈光力，并为不同屈光力的角膜屈光手术做好手术规划。
