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放射科工作人员的氧化应激。

Oxidative stress in radiology staff.

机构信息

Esfahan Payam-E-Noor University of Sciences, Esfahan, Iran.

出版信息

Environ Toxicol Pharmacol. 2005 Jul;20(1):215-8. doi: 10.1016/j.etap.2005.01.005. Epub 2005 Feb 25.

Abstract

UNLABELLED

Excessive production of reactive oxygen species has been observed following acute and chronic exposure to radiation in animal models which can lead to several detrimental and irreversible outcomes in vital organs. Aim of this study was to determine the oxidative stress status in radiology unit workers which are exposed to persistent low-dose radiation.

METHODS

: A group of 32 radiology unit employees along with 32 sex- and age-matched hospital workers, not exposed to low-dose radiation were recruited from two separate hospitals for the study. Exposed subjects showed higher levels of lipid peroxidation (P=0.009), total antioxidant capacity (P=0.0006) and thiol groups (P=0.03). It is concluded that occupationally exposed individuals are oxidatively stressed and precautions such as antioxidant therapy seems reasonable.

摘要

目的

本研究旨在确定放射科工作人员在持续低剂量辐射下的氧化应激状态。

方法

从两家医院招募了 32 名放射科工作人员和 32 名性别和年龄匹配的非低剂量辐射暴露的医院工作人员作为研究对象。暴露组的脂质过氧化水平较高(P=0.009),总抗氧化能力(P=0.0006)和巯基基团(P=0.03)较高。

结论

职业暴露个体处于氧化应激状态,采取抗氧化治疗等预防措施似乎是合理的。

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