Department of Urology, Center for Kidney Research, Children's Hospital at Westmead, School of Public Health, Westmead, New South Wales, Australia.
J Urol. 2011 Sep;186(3):1048-52. doi: 10.1016/j.juro.2011.04.104. Epub 2011 Jul 23.
We evaluated quality of life in children with urinary incontinence using a disease specific tool (Pediatric Incontinence Questionnaire) and determined factors that decrease quality of life in affected children.
The Pediatric Incontinence Questionnaire was self-administered by children 6 to16 years old with urinary incontinence while attending outpatient clinics at a tertiary pediatric hospital in Australia between October 2009 and May 2010. A weighted summative quality of life score with a range of 1.75 to 7 (7 being lowest quality of life) was generated, and patient characteristics (age, gender, ethnicity, symptom severity) were evaluated as potential predictors.
Of 146 children invited to participate 138 consented (response rate 95%). About half of the participants (77) were boys, and mean patient age was 10 years. Girls had a lower quality of life than boys (mean score 3.60 vs 3.31, 95% CI 0.10-0.57, p=0.04), and nonwhite children had a lower quality of life than white children (3.97 vs 3.35, 95% CI 0.23-0.99, p<0.01). Older age (r=0.21, p=0.01) but not increasing symptom severity (r=0.15, p=0.09) or underlying chronic disease (difference 0.12, p=0.91) was correlated to decreased quality of life. Multivariate regression analysis demonstrated that older age, nonwhite ethnicity and female gender were independent predictors of decreased quality of life.
Older age, female gender and nonwhite ethnicity are associated with a lower disease specific quality of life in children with urinary incontinence. Clinicians need to be aware of the differential effect of urinary incontinence in children of different ages and ethnic backgrounds.
我们使用一种特定疾病的工具（小儿尿失禁问卷）评估了患有尿失禁的儿童的生活质量，并确定了降低受影响儿童生活质量的因素。
2009 年 10 月至 2010 年 5 月期间，在澳大利亚一家三级儿科医院的门诊，我们邀请了 6 至 16 岁患有尿失禁的儿童使用小儿尿失禁问卷进行自我评估。生成了一个加权求和的生活质量评分，范围为 1.75 至 7（7 表示生活质量最低），并评估了患者特征（年龄、性别、种族、症状严重程度）作为潜在的预测因素。
共邀请了 146 名儿童参加，其中 138 名同意（应答率为 95%）。约一半的参与者（77 名）为男孩，平均患者年龄为 10 岁。女孩的生活质量低于男孩（平均评分 3.60 与 3.31，95%CI0.10-0.57，p=0.04），非白种儿童的生活质量低于白种儿童（3.97 与 3.35，95%CI0.23-0.99，p<0.01）。年龄较大（r=0.21，p=0.01）而不是症状严重程度增加（r=0.15，p=0.09）或潜在慢性疾病（差异 0.12，p=0.91）与生活质量下降相关。多变量回归分析表明，年龄较大、非白种裔和女性是生活质量下降的独立预测因素。
年龄较大、女性和非白种裔与患有尿失禁的儿童的特定疾病生活质量较低相关。临床医生需要意识到尿失禁在不同年龄和种族背景的儿童中的不同影响。
