Mannina Edward M, Pejavar Sunanda M, Glastonbury Christine M, van Zante Annemieke, Wang Steven J, Yom Sue S
Department of Radiation Oncology, University of California San Francisco, 1600 Divisadero Street, P.O. Box 1708, Suite H-1031, San Francisco, CA 94143, USA.
Int J Otolaryngol. 2011;2011:928240. doi: 10.1155/2011/928240. Epub 2011 Jul 14.
Diagnostic workup of metastatic head and neck squamous cell carcinoma of unknown primary site has traditionally included CT and/or MRI imaging and endoscopic biopsies. Routine bilateral tonsillectomy is highly controversial and the role of PET/CT is evolving, both for identification of potential primary sites and the detection of distant metastases. We report a case of cervical nodal metastasis of squamous cell carcinoma from an unknown primary site, in which dual-modality PET/CT led to the unexpected diagnosis of synchronous bilateral tonsillar cancers. In addition, PET/CT correctly distinguished pulmonary sarcoidosis from metastatic disease in this patient.
传统上，对原发部位不明的转移性头颈部鳞状细胞癌进行诊断性检查时，包括CT和/或MRI成像以及内镜活检。常规双侧扁桃体切除术极具争议，PET/CT在识别潜在原发部位和检测远处转移方面的作用也在不断演变。我们报告一例原发部位不明的鳞状细胞癌颈部淋巴结转移病例，其中双模态PET/CT意外诊断出同步双侧扁桃体癌。此外，PET/CT在该患者中正确区分了肺结节病和转移性疾病。
