Key Laboratory of Ethnic Medicine Resource Chemistry, State Ethnic Affairs Commission & Ministry of Education, Yunnan Nationalities University, Kunming, Yunnan 650031, China.
Chem Soc Rev. 2012 Jan 21;41(2):560-72. doi: 10.1039/c1cs15127d. Epub 2011 Jul 25.
Transition metal-catalyzed cross-coupling reactions have been established as one of the most powerful tools for the construction of C-C and C-X bonds. In this context, the development of novel metal-catalyzed cross-coupling processes that do not require stoichiometric organometallic reagents is particularly attractive. Recently, N-tosylhydrazones have emerged as a new type of versatile coupling partners for transition metal-catalyzed cross-coupling reactions as well as metal-free cross-coupling reactions, and have attracted increasing attention. This tutorial review summarizes recent important developments in this area with N-tosylhydrazones as versatile coupling partners.
过渡金属催化的交叉偶联反应已成为构建 C-C 和 C-X 键的最有力工具之一。在这种情况下，开发新型的不需要化学计量的有机金属试剂的金属催化交叉偶联过程特别有吸引力。最近，N-对甲苯磺酰腙作为一种新型的多功能偶联试剂，已经成为过渡金属催化交叉偶联反应以及无金属交叉偶联反应的新选择，引起了越来越多的关注。本综述总结了 N-对甲苯磺酰腙作为多功能偶联试剂在这一领域的最新重要进展。
