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为对左洛啡烷、丁卡因和多粘菌素产生抗性而筛选出的大肠杆菌表面改变突变体的脂质和脂多糖组成

Lipid and lipopolysaccharide composition of Escherichia coli surface-altered mutants selected for resistance to levallorphan, tetracaine, and polymyxin.

作者信息

Dame J B, Shapiro B M

出版信息

J Bacteriol. 1979 Feb;137(2):1043-7. doi: 10.1128/jb.137.2.1043-1047.1979.

Abstract

Certain mutants of Escherichia coli with an altered permeability barrier have an essentially normal lipopolysaccharide, fatty acid, and phospholipid content, with a slight increase in the membrane protein:lipid ratio. The phospholipid metabolism of the lev and tec strains shows an abnormal response to growth in the selective agents levallorphan and tetracaine, respectively.

摘要

某些具有改变的通透性屏障的大肠杆菌突变体具有基本正常的脂多糖、脂肪酸和磷脂含量,膜蛋白与脂质的比例略有增加。lev和tec菌株的磷脂代谢分别显示出对选择性试剂左洛啡烷和丁卡因生长的异常反应。

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