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19 岁女性在运动时发生先天性单冠状动脉口畸形导致的意外猝死。

Unexpected sudden death of a 19-year-old female with congenital single coronary artery ostium during exertion.

机构信息

Department of Forensic Medicine, Chonbuk National University Medical School, Jeonju, Korea.

出版信息

Yonsei Med J. 2011 Sep;52(5):856-8. doi: 10.3349/ymj.2011.52.5.856.

DOI:10.3349/ymj.2011.52.5.856
PMID:21786453
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3159929/
Abstract

Coronary artery anomalies are associated often with myocardial ischemia or sudden cardiac death. A 19-year-old woman who participated in an exertive game lost consciousness upon one such exertion. She was taken to a hospital where she died on the same day. An autopsy revealed that she had bifurcated coronary arteries, which arose from one coronary ostium in the left sinus of Valsalva. The right coronary artery arose from the left sinus and traveled between the aorta and the pulmonary trunk. The heart as well as the cardiac conduction system depended exclusively on the single coronary artery ostium for oxygenated blood supply, and the unbalanced blood distribution on her exertion probably led to sudden cardiac death. The case highlights the medicolegal importance of unexpected sudden cardiac death related to an anomalous origin of the coronary arteries.

摘要

冠状动脉异常常与心肌缺血或心源性猝死有关。一名 19 岁的女性在进行剧烈运动时突然失去意识。她被送往医院,当天死亡。尸检显示她的冠状动脉呈双叉状,发自左窦的单一冠状动脉开口。右冠状动脉发自左窦,穿行于主动脉和肺动脉干之间。心脏和心脏传导系统完全依赖单一冠状动脉开口供氧,她在剧烈运动时的血液分布不平衡可能导致心源性猝死。本病例强调了与冠状动脉异常起源相关的意外心源性猝死的法医学重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f224/3159929/28e850054a04/ymj-52-856-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f224/3159929/550f519986b0/ymj-52-856-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f224/3159929/28e850054a04/ymj-52-856-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f224/3159929/550f519986b0/ymj-52-856-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f224/3159929/28e850054a04/ymj-52-856-g002.jpg

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本文引用的文献

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Isr Med Assoc J. 2007 Aug;9(8):624-5.
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Coronary artery anomalies and sudden death.冠状动脉异常与猝死
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Clinical profile of congenital coronary artery anomalies with origin from the wrong aortic sinus leading to sudden death in young competitive athletes.源于异常主动脉窦导致年轻竞技运动员猝死的先天性冠状动脉异常的临床特征
与孤立性动脉导管未闭相关的冠状动脉起源异常发生率增加。
Pediatr Cardiol. 2013 Apr;34(4):907-11. doi: 10.1007/s00246-012-0569-0. Epub 2012 Nov 11.
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4
Coronary arteries from a single coronary ostium in the right coronary sinus: a previously unreported anatomy.发自右冠状动脉窦单一冠状动脉开口的冠状动脉:一种此前未报道过的解剖结构。
Heart. 2000 May;83(5):E9. doi: 10.1136/heart.83.5.e9.
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Anomalous origin of coronary arteries and risk of sudden death: a study based on an autopsy population of congenital heart disease.冠状动脉异常起源与猝死风险:一项基于先天性心脏病尸检人群的研究
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