Ohshima T, Lin Z, Sato Y
Department of Legal Medicine, Kanazawa University Faculty of Medicine, Japan.
Forensic Sci Int. 1996 Sep 30;82(2):177-81. doi: 10.1016/0379-0738(96)01993-7.
A rare autopsy case of a 12-year-old male with a single coronary artery is reported in which he suddenly and unexpectedly died after a brief period of physical and mental excitation. The single coronary artery originated from the left aortic sinus, then branched out the left circumflex artery and afterwards descended as the left anterior descending artery, while the right coronary artery originated almost at a right angle from the left anterior descending artery. The entire heart as well as the cardiac conduction system depended exclusively on the single coronary artery for oxygenated blood supply, and the unbalanced blood distribution on his exertion probably led to sudden cardiac death. Moreover, in this case, both the deceased's mother (at the age of 20 years) and grandmother on the mother's side died suddenly, thus suggesting a possibility of maternal transmission of this congenital anomaly in his family.
报告了一例罕见的12岁男性单冠状动脉尸检病例，该患者在经历短暂的身心兴奋后突然意外死亡。单冠状动脉起源于左主动脉窦，随后分支为左旋支动脉，然后作为左前降支动脉下行，而右冠状动脉几乎以直角从左前降支动脉发出。整个心脏以及心脏传导系统完全依赖单冠状动脉供应含氧血液，其运动时血液分布不均衡可能导致心源性猝死。此外，在该病例中，死者的母亲（20岁）和外祖母均突然死亡，因此提示该家族中这种先天性异常可能存在母系遗传。
