Department of Pediatrics, University of Catania, Catania, Italy.
Int Rev Immunol. 2011 Aug;30(4):219-31. doi: 10.3109/08830185.2011.602443.
Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten in genetically susceptible individuals. It is one of the most common lifelong disorders on a worldwide basis. Celiac enteropathy is the final consequence of an abnormal immune reaction, showing features of both an innate and an adaptive response to gluten prolamins. The clinical spectrum is wide, including cases with either typical intestinal or atypical extraintestinal features, and silent forms. The only available treatment consists in dietary exclusion of grains containing gluten. New pharmacological treatment are currently under scrutiny.
乳糜泻（CD）是一种由遗传易感个体摄入麸质引起的免疫介导的肠病。它是全球范围内最常见的终身疾病之一。乳糜泻肠病是异常免疫反应的最终结果，表现出对麦醇溶蛋白既有先天又有适应性反应的特征。临床谱很广，包括典型的肠道或非典型的肠外特征以及无症状的病例。唯一可用的治疗方法是饮食中排除含有麸质的谷物。新的药物治疗方法目前正在审查中。
