Department of General Internal Medicine, Division of Psychosomatic Medicine, Inselspital, Bern University Hospital, CH-3010 Bern, Switzerland.
BMC Musculoskelet Disord. 2011 Jul 25;12:174. doi: 10.1186/1471-2474-12-174.
Hypersensitivity of the central nervous system is widely present in pain patients and recognized as one of the determinants of chronic pain and disability. Electronic pressure algometry is often used to explore aspects of central hypersensitivity. We hypothesized that a simple pain provocation test with a clothes peg provides information on pain sensitivity that compares meaningfully to that obtained by a well-established electronic pressure algometer. "Clinically meaningful" was defined as a medium (r = 0.3-0.5) or high (r > 0.5) correlation coefficient according to Cohen's conventions.
We tested 157 in-patients with different pain types. A calibrated clothes peg was applied for 10 seconds and patients rated the pain intensity on a 0 to 10 numerical rating scale. Pressure pain detection threshold (PPdt) and pressure pain tolerance threshold (PPtt) were measured with a standard electronic algometer. Both methods were performed on both middle fingers and ear lobes. In a subgroup of 47 patients repeatability (test-retest reliability) was calculated.
Clothes peg values correlated with PPdt values for finger testing with r = -0.54 and for earlobe testing with r = -0.55 (all p-values < 0.001). Clothes peg values also correlated with PPtt values for finger testing with r = -0.55 (p < 0.001). Test-retest reliability (repeatability) showed equally stable results for clothes peg algometry and the electronic algometer (all r-values > 0.89, all p-values < 0.001).
Information on pain sensitivity provided by a calibrated clothes peg and an established algometer correlate at a clinically meaningful level.
中枢神经系统过敏在疼痛患者中广泛存在,被认为是慢性疼痛和残疾的决定因素之一。电子压痛测定法常用于探索中枢敏化的各个方面。我们假设,使用衣夹进行简单的疼痛激发测试,可以提供有意义的疼痛敏感性信息,与经过充分验证的电子压痛测定法相比具有可比性。“有临床意义”根据科恩的惯例定义为中等(r = 0.3-0.5)或高度(r>0.5)相关系数。
我们测试了 157 名患有不同类型疼痛的住院患者。用校准的衣夹夹 10 秒钟,患者用 0 到 10 的数字评分量表评定疼痛强度。使用标准电子压痛测定仪测量压痛感觉阈(PPdt)和压痛耐量阈(PPtt)。两种方法均在中指和耳垂上进行。在 47 名患者的亚组中计算了重复性(测试-再测试可靠性)。
衣夹值与手指测试的 PPdt 值相关,r 值为-0.54,与耳垂测试的 r 值为-0.55(均 p 值<0.001)。衣夹值与手指测试的 PPtt 值也相关,r 值为-0.55(p<0.001)。测试-再测试可靠性(重复性)显示衣夹压痛测定法和电子压痛测定法的结果同样稳定(所有 r 值>0.89,均 p 值<0.001)。
校准衣夹和经过充分验证的压痛测定仪提供的疼痛敏感性信息在临床上具有有意义的相关性。