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特发性大动脉炎:一种被低估的血管炎。

Idiopathic aortitis: an underrecognized vasculitis.

出版信息

Arthritis Res Ther. 2011 Jul 22;13(4):119. doi: 10.1186/ar3389.

Abstract

Aortitis is a general term denoting inflammation of the aortic wall. Various infectious and non-infectious diseases can be complicated by aortitis; in addition, isolated idiopathic aortitis has also been described. In a 12-year nationwide Danish population-based study, the prevalence of aortitis among 1,210 resected thoracic aorta samples was 6.1%, with nearly three-quarters of cases being idiopathic. Identified risk factors for aortitis included advanced age, a history of connective tissue disease, diabetes mellitus, and heart valve pathology. As in virtually all pathological studies, this study has a bias toward reporting the most severe cases of aortitis requiring surgical repair.

摘要

主动脉炎是一个统称,指的是主动脉壁的炎症。各种感染性和非感染性疾病都可能并发主动脉炎;此外,也有描述孤立性特发性主动脉炎。在一项为期 12 年的丹麦全国基于人群的研究中,1210 个切除的胸主动脉样本中主动脉炎的患病率为 6.1%,其中近四分之三的病例为特发性。已确定的主动脉炎危险因素包括年龄较大、结缔组织疾病病史、糖尿病和心脏瓣膜病。与几乎所有的病理研究一样,本研究存在偏向报告需要手术修复的最严重的主动脉炎病例的偏差。

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