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尿路感染后孤立性腹主动脉炎

Isolated Abdominal Aortitis Following a Urinary Tract Infection.

作者信息

Mustafa Ala, Weilg Pablo, Young Larry, Anzalone Christopher, Hagau Denisa

机构信息

Internal Medicine, MercyOne North Iowa Medical Center, Mason City, USA.

Rheumatology, Boston Medical Center, Boston, USA.

出版信息

Cureus. 2021 Oct 19;13(10):e18902. doi: 10.7759/cureus.18902. eCollection 2021 Oct.

DOI:10.7759/cureus.18902
PMID:34804739
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8599397/
Abstract

A 49-year-old female with a history of sporadic episodes of scleritis was initially seen by her primary care physician (PCP) due to a two-day history of cramping abdominal pain, new elevated high blood pressure, increased urinary frequency, and urgency. The patient was diagnosed with an acute cystitis supported by a positive urine culture for a pan sensitive ; however, after two courses of antibiotics as an outpatient, her blood pressure (BP) remained markedly elevated, and her abdominal pain got worse which prompted a computed tomography (CT) abdomen and pelvis with contrast revealing inflammatory changes consistent with aortitis. The diagnosis was supported by a magnetic resonance angiography (MRA) which showed wall thickening and enhancement extending for approximately 4.8 cm involving the abdominal aortic wall just prior to the bifurcation. An extensive work up including CTA, US doppler of four-limbs, and fluorodeoxyglucose (FDG)-positron emission tomography (PET) confirmed the isolated abdominal aortitis. After infectious etiologies were ruled out, the patient was started on prednisone 60 mg daily which resulted in marked improvement of her symptoms. After a four-month taper of steroids, the patient had complete resolution of her symptoms, with no signs of recurrence.

摘要

一名49岁女性,有散发性巩膜炎病史,因两天的腹部绞痛、新出现的高血压、尿频和尿急,最初由她的初级保健医生(PCP)接诊。患者尿培养对泛敏感菌呈阳性,被诊断为急性膀胱炎;然而,作为门诊患者接受两个疗程的抗生素治疗后,她的血压(BP)仍显著升高,腹痛加剧,这促使进行了腹部和盆腔增强计算机断层扫描(CT),显示与主动脉炎一致的炎症改变。磁共振血管造影(MRA)支持该诊断,显示在分叉前约4.8厘米处腹主动脉壁增厚并强化,累及腹主动脉壁。包括CT血管造影(CTA)、四肢超声多普勒和氟脱氧葡萄糖(FDG)-正电子发射断层扫描(PET)在内的广泛检查证实为孤立性腹主动脉炎。排除感染性病因后,患者开始每天服用60毫克泼尼松,症状明显改善。经过四个月的类固醇减量,患者症状完全缓解,无复发迹象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70a4/8599397/2f7355bfa31d/cureus-0013-00000018902-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70a4/8599397/7492681999a8/cureus-0013-00000018902-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70a4/8599397/2f7355bfa31d/cureus-0013-00000018902-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70a4/8599397/7492681999a8/cureus-0013-00000018902-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70a4/8599397/2f7355bfa31d/cureus-0013-00000018902-i02.jpg

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本文引用的文献

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Aortitis and periaortitis: The puzzling spectrum of inflammatory aortic diseases.主动脉炎和主动脉周围炎:炎症性主动脉疾病的复杂谱系。
Presse Med. 2020 Apr;49(1):104018. doi: 10.1016/j.lpm.2020.104018. Epub 2020 Mar 28.
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Mechanism and biomarkers in aortitis--a review.巨细胞动脉炎的发病机制和生物标志物——综述。
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