School of Human Ecology, Louisiana State University Agricultural Center, Baton Rouge, LA 70803, USA.
J Clin Densitom. 2011 Apr-Jun;14(2):116-21. doi: 10.1016/j.jocd.2011.02.002.
Quantitative ultrasound (QUS) race-specific normative reference data are not available for accurate calculation of Z-scores. The primary aims of this study were (1) to develop a race-specific QUS reference database for white and black females and to compare estimated fracture risk between these 2 racial groups and (2) to compare stiffness index (SI) values of white females in this study to manufacturer-obtained values. Subjects included 1111 females (31% black), aged 20-85 yr (52 ± 19 yr), with a mean SI score of 93.7 ± 20.1. White females, aged 20-39 yr (n=213), were used to calculate T-scores, whereas Z-scores were age and race specific. Black females had significantly higher SI scores than white females (p<0.001). White females aged 50+ yr in this study had significantly higher SI scores compared with manufacturer-derived values. Results highlight the need for population- and race-specific normative data when using QUS as a screening tool for identifying high fracture risk.
定量超声(QUS)种族特异性参考数据尚不可用于准确计算 Z 分数。本研究的主要目的是:(1)为白人和黑人女性建立种族特异性 QUS 参考数据库,并比较这两个种族群体的估计骨折风险;(2)比较本研究中白人女性的硬度指数(SI)值与制造商获得的值。研究对象包括 1111 名女性(31%为黑人),年龄 20-85 岁(52±19 岁),平均 SI 评分为 93.7±20.1。白人女性(年龄 20-39 岁,n=213)用于计算 T 评分,而 Z 评分则是年龄和种族特异性的。黑人女性的 SI 评分显著高于白人女性(p<0.001)。与制造商提供的数据相比,本研究中年龄在 50 岁以上的白人女性的 SI 评分显著升高。结果强调了在使用 QUS 作为识别高骨折风险的筛查工具时,需要使用人群和种族特异性的参考数据。