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加纳 Obuasi 市居民儿童铅和汞神经毒性健康风险评估。

Evaluation of lead and mercury neurotoxic health risk by resident children in the Obuasi municipality, Ghana.

机构信息

CSIR - Water Research Institute, P.O. Box AH 38, Achimota Accra, Ghana; Centre for Environmental Impact Analysis, P.O. Box AD 738, Cape Coast, Ghana.

出版信息

Environ Toxicol Pharmacol. 2010 May;29(3):209-12. doi: 10.1016/j.etap.2010.01.001. Epub 2010 Jan 25.

Abstract

This study assesses neurotoxic effects associated with exposure to lead and mercury in borehole, tap and surface water by resident children in the Obuasi municipality in accordance with USEPA risk assessment guidelines. From the results of the study, the hazard quotient for oral ingestion of mercury in tap water in Obuasi is 7.4 and 15 respectively via both central tendency exposure (CTE) and reasonable maximum exposure (RME) parameters, respectively. This means that approximately 7 and 15 (by both CTE and RME parameters, respectively) resident children in Obuasi are likely to show neurologic effects associated with exposure to mercury and lead such as increased nervousness, loss of memory and/or decrease in concentration, impaired writing ability and tremor.

摘要

本研究按照美国环保署风险评估指南,评估了奥布阿西市居民儿童在饮用井水、自来水和地表水时接触铅和汞的神经毒性影响。根据研究结果,奥布阿西市自来水中汞的经口摄入危害系数分别为 7.4 和 15,这是通过中心趋势暴露(CTE)和合理最大暴露(RME)参数得出的。这意味着,奥布阿西市大约有 7 和 15 的(分别通过 CTE 和 RME 参数)居民儿童可能会出现与接触汞和铅相关的神经效应,如紧张增加、记忆力丧失和/或注意力下降、书写能力受损和震颤。

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