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山西省2009 - 2010年流感/新型甲型H1N1流感病原学监测分析

[Analysis on the etiological surveillance of influenza/novel influenza A (H1N1) from 2009-2010 in Shanxi Province].

作者信息

Ren Bin-zhi, Wang Nai-chang, Feng Jun-jun, Zhao Rong, Zhang Fan-fei

机构信息

Shanxi Center for Disease Control and Prevention, Taiyuan 030012, China.

出版信息

Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2011 Feb;25(1):20-2.

PMID:21789846
Abstract

OBJECTIVE

To study the epidemical characteristics of influenza/novel influenza A (H1N1) in Shanxi province from 2009 to 2010, and to provide scientific foundations for predicting and controlling the pandemic outbreak of influenza/novel influenza A (H1N1) effectively.

METHODS

All samples were collected from cases that resemble influenza cases in sentinel hospital and influenza outbreak. The influenza were detected by PCR and isolated by MDCK cell culture method. Finally, Shanxi province surveillance data from May, 2009 to April, 2010 of influenza like illness (ILI) cases and pathogen detections were analyzed.

RESULTS

In Shanxi province, influenza viruses kept activation in whole year. The predominant pandemic strain in 2009 was novel influenza A (H1N1) virus. The strong peak was around November, 2009 [positive rate: 58.1%, novel influenza A ( H1N1) of the total: 88.1%]. As well, the people infected influenza caused by novel influenza A (H1N1) were mainly under 59-year-old, and the higher positive rates were concentrated in the people from 5-year-old to 24-year-old. In 2010, influenza B (Victoria) viruses were mainly detected from clinical specimens and became the dominant strain.

CONCLUSION

Surveillance of Influenza liue illnes, (ILI) and etiology, which can promptly reflect the influenza epidemic situation, play a significant role for understanding epidemic rule of influenza/novel influenza A (H1N1).

摘要

目的

研究山西省2009 - 2010年流感/新型甲型H1N1流感的流行特征,为有效预测和控制流感/新型甲型H1N1流感大流行疫情提供科学依据。

方法

所有样本均采集自哨点医院疑似流感病例及流感暴发疫情。采用PCR法检测流感病毒,并用MDCK细胞培养法进行分离。最后,对山西省2009年5月至2010年4月流感样病例(ILI)监测数据及病原体检测结果进行分析。

结果

山西省全年流感病毒均有活动。2009年主要流行株为新型甲型H1N1流感病毒。强峰期在2009年11月左右[阳性率:58.1%,新型甲型H1N1流感占总阳性的88.1%]。此外,新型甲型H1N1流感感染者主要为59岁以下人群,较高阳性率集中在5岁至24岁人群。2010年,临床标本中主要检测出乙型(维多利亚)流感病毒并成为优势毒株。

结论

流感样病例(ILI)监测及病原学监测能够及时反映流感疫情,对了解流感/新型甲型H1N1流感流行规律具有重要作用。

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