Bian Li-hua, Wang Xiao-li, Guo Yi-fan, Wu Xiao-zhou, Song Lei, Liu Hong-tu
Department of Obstetrics and Gynaecology, Chinese PLA General Hospital, Beijing 100853, China.
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2011 Feb;25(1):63-5.
To observe the infection of the high risk human papillomavirus (HPV) in the specimen of the small cell neuroendocrine carcinoma of the uterine cervix (SCNEC).
We extracted the nucleic acids in the formalin-fixed and paraffin-embedded specimen from a 33-year-old patient diagnosed as small cell neuroendocrine carcinoma of uterine cervix and detected the HPV genotype with the nested PCR.
We identified HPV18, a high-risk genotype, in the specimen.
The HPV detection with the nested PCR was available for identification of the HPV genotype(s) in the paraffin-embedded specimens of small cell neuroendocrine carcinoma of the uterine cervix with a high accuracy and sensitivity.
观察子宫颈小细胞神经内分泌癌（SCNEC）标本中高危型人乳头瘤病毒（HPV）的感染情况。
我们从一名被诊断为子宫颈小细胞神经内分泌癌的33岁患者的福尔马林固定石蜡包埋标本中提取核酸，并用巢式PCR检测HPV基因型。
我们在标本中鉴定出高危基因型HPV18。
巢式PCR检测HPV可用于准确、灵敏地鉴定子宫颈小细胞神经内分泌癌石蜡包埋标本中的HPV基因型。
