梅格斯综合征伴卵巢硬化性间质瘤患者血清癌抗原 125 水平升高。
Meigs' syndrome with elevated serum cancer antigen 125 levels in a case of ovarian sclerosing stromal tumor.
机构信息
Department of Surgical Pathology, Changhua Christian Hospital, Changhua, Taiwan.
出版信息
Taiwan J Obstet Gynecol. 2011 Jun;50(2):196-200. doi: 10.1016/j.tjog.2011.01.011.
OBJECTIVE
Meigs' syndrome presenting as an ovarian tumor with elevated serum cancer antigen 125 (CA 125) levels is unusual. Only 37 cases have been reported, including three cases of ovarian sclerosing stromal tumor (SCT). Many reports have suggested that the presence of ascites is the major factor inducing mesothelial expression of CA 125.
CASE REPORT
An 18-year-old woman presented with massive ascites, elevated serum CA 125 levels, and radiographic evidence of ovarian tumor. The histological and immunohistochemical examinations revealed a benign SCT.
CONCLUSION
SCT is a benign ovarian tumor and complete excision is curative. We also review all 37 cases and discuss possible mechanisms of Meigs' syndrome and elevated serum CA 125 level.
目的
以卵巢肿瘤伴血清癌抗原 125（CA 125）水平升高为表现的 Meigs 综合征并不常见。仅有 37 例报道，其中包括 3 例卵巢硬化性间质瘤（SCT）。许多报道表明，腹水的存在是诱导间皮细胞表达 CA 125 的主要因素。
病例报告
一名 18 岁女性因大量腹水、血清 CA 125 水平升高和影像学证据的卵巢肿瘤就诊。组织学和免疫组织化学检查显示良性 SCT。
结论
SCT 是一种良性卵巢肿瘤，完整切除即可治愈。我们还回顾了所有 37 例病例，并讨论了 Meigs 综合征和血清 CA 125 水平升高的可能机制。
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