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玻璃体内注射培加他尼治疗视网膜静脉阻塞继发的难治性黄斑水肿。

Intravitreal pegaptanib for refractory macular edema secondary to retinal vein occlusion.

作者信息

Udaondo Patricia, Garcia-Delpech Salvador, Salom David, Garcia-Pous Maria, Diaz-Llopis Manuel

机构信息

Nuevo Hospital Universitario y Politecnico La Fe, Valencia, Spain.

出版信息

Clin Ophthalmol. 2011;5:941-4. doi: 10.2147/OPTH.S18873. Epub 2011 Jul 7.

DOI:10.2147/OPTH.S18873
PMID:21792283
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3141857/
Abstract

PURPOSE

To assess the efficacy of intravitreal Pegaptanib sodium (Macugen(®)) injection in the management of refractory macular edema secondary to branch retinal vein occlusion.

METHODS

This is a prospective, nonrandomized, interventional case series. Five eyes of five patients with macular edema refractory to either bevacizumab or triamcinolone were treated with intravitreal injection of Pegaptanib sodium.

RESULTS

After three months follow-up, both visual acuity and macular edema, measured by optical coherence tomography and fluorescence angiography, dramatically improved.

CONCLUSION

Pegaptanib sodium is a safe and efficacy treatment for macular edema secondary to branch retinal vein occlusion.

摘要

目的

评估玻璃体内注射培加他汀钠（Macugen(®)）治疗视网膜分支静脉阻塞继发难治性黄斑水肿的疗效。

方法

这是一个前瞻性、非随机、干预性病例系列。对5例黄斑水肿患者的5只眼睛进行了治疗，这些患者对贝伐单抗或曲安奈德治疗无效，采用玻璃体内注射培加他汀钠进行治疗。

结果

经过3个月的随访，通过光学相干断层扫描和荧光血管造影测量，视力和黄斑水肿均有显著改善。

结论

培加他汀钠是治疗视网膜分支静脉阻塞继发黄斑水肿的一种安全有效的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5738/3141857/03736f709695/opth-5-941f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5738/3141857/03736f709695/opth-5-941f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5738/3141857/03736f709695/opth-5-941f1.jpg

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Short-term efficacy of intravitreal triamcinolone acetonide for macular edema secondary to retinal vein occlusion that is refractory to intravitreal bevacizumab.玻璃体内注射曲安奈德治疗对玻璃体内注射贝伐单抗耐药的视网膜静脉阻塞继发黄斑水肿的短期疗效
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Ranibizumab for macular edema following branch retinal vein occlusion: six-month primary end point results of a phase III study.雷珠单抗治疗视网膜分支静脉阻塞继发黄斑水肿：一项 III 期研究的 6 个月主要终点结果。
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