Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei 230032, Anhui. People's Republic of China
Rheumatol Int. 2012 Sep;32(9):2707-14. doi: 10.1007/s00296-011-2043-3. Epub 2011 Jul 27.
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organs. Because of double damages of body and mind, SLE patients are in a potential risk of suicide. Many factors may contribute to the occurrence of suicide in SLE: socioeconomic factors, medical factors, mental health, family support and coping style. This study aims to investigate the prevalence and correlates of suicidal ideation in SLE inpatients in China in order to determine whether they had risk of suicide, and if so, what factors should be paid more attention to prevent suicide in wards. A total of 285 SLE patients were interviewed with questionnaires on suicidal ideation and socio-demographic characteristics, Beck Depression Inventory (BDI), Family APGAR and Trait Coping Style Questionnaire (TCSQ). Disease activity was assessed with SLE Disease Activity Index. The other medical information was collected from the patients' medical records. In total, 34.4% of SLE patients had current suicidal ideation. Significant individual risk factors for current suicidal ideation in SLE patients included having religious belief, heavy self-reported financial burdens, long duration of SLE, low level of family functioning and negative coping style. And in the presence of these risk factors, being separated, divorced or widowed, having premorbid suicidal ideation and depression were independent predictors of suicidal ideation. In summary, the rate of suicidal ideation in SLE patients in China is higher than that in other countries. Factors that contribute to risk of suicidal ideation include social and cultural domains and physical and psychological health. Although the association of suicidal ideation to religions and medical factors is still to be investigated, these findings may give some references to suicide prevention efforts for SLE patients in China.
系统性红斑狼疮（SLE）是一种影响多个器官的慢性自身免疫性疾病。由于身心的双重伤害，SLE 患者存在潜在的自杀风险。许多因素可能导致 SLE 患者发生自杀：社会经济因素、医疗因素、心理健康、家庭支持和应对方式。本研究旨在调查中国 SLE 住院患者自杀意念的发生率及其相关因素，以确定他们是否有自杀风险，如果有，哪些因素应在病房中更加强调以预防自杀。共对 285 名 SLE 患者进行了自杀意念和社会人口学特征、贝克抑郁量表（BDI）、家庭 APGAR 和特质应对方式问卷（TCSQ）的问卷调查。疾病活动度采用 SLE 疾病活动指数进行评估。其他医疗信息从患者的病历中收集。共有 34.4%的 SLE 患者存在当前的自杀意念。SLE 患者当前自杀意念的显著个体危险因素包括有宗教信仰、沉重的自我报告经济负担、SLE 病程长、家庭功能水平低和消极应对方式。在存在这些危险因素的情况下，离异、丧偶或分居、有自杀意念和抑郁的前驱期是自杀意念的独立预测因素。总之，中国 SLE 患者的自杀意念发生率高于其他国家。导致自杀意念风险的因素包括社会文化领域以及身心健康。尽管宗教和医疗因素与自杀意念的关联仍有待调查，但这些发现可能为中国 SLE 患者的自杀预防工作提供一些参考。
