Department of Paediatrics, Rijnstate Hospital Arnhem, Arnhem, The Netherlands.
Pediatr Infect Dis J. 2011 Dec;30(12):1107-9. doi: 10.1097/INF.0b013e31822cca1f.
We studied the potential benefits of introducing a rapid enterovirus molecular test in children with enterovirus meningitis. The 2 groups of pediatric patients were comparable with respect to clinical and laboratory data, but differed in availability of enterovirus test results. In the control group, the results were available within 3 to 7 days, whereas in the study group, rapid enterovirus molecular test results were available within 3 to 24 hours. The median duration of hospitalization and the duration of antibiotics were significantly reduced to, respectively, 2 days and 1 day in the study group when compared with the control group (P < 0.001). Mean costs per patient calculation showed an average reduction of more than US $1450 (P < 0.001).
我们研究了在患有肠道病毒脑膜炎的儿童中引入快速肠道病毒分子检测的潜在益处。这两组儿科患者在临床和实验室数据方面具有可比性，但在获得肠道病毒检测结果方面存在差异。在对照组中，结果可在 3 至 7 天内获得，而在研究组中，快速肠道病毒分子检测结果可在 3 至 24 小时内获得。与对照组相比，研究组患者的住院时间中位数和抗生素使用时间分别显著缩短至 2 天和 1 天（P < 0.001）。每位患者的平均费用计算显示，平均减少超过 1450 美元（P < 0.001）。
