Department of Pediatrics, Division of Pediatric Gastroenterology and Nutrition, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Clin Auton Res. 2011 Dec;21(6):419-23. doi: 10.1007/s10286-011-0130-x. Epub 2011 Jul 28.
INTRODUCTION/RESULTS: In 17 patients, chronic idiopathic nausea was associated with orthostatic intolerance (OI) by abnormal tilt table tests (88%) or gastric dysrhythmias (71%). After fludrocortisone treatment, there was >26% nausea improvement in 71%, 1-25% in 6%, and no improvement in 24%. In six subjects, EGGs repeated after >50% nausea improvement all remained to be abnormal, suggesting nausea is independent of gastric dysrhythmias.
Association of EGG abnormalities and OI in this subset of nausea patients suggests a generalized disturbance of autonomic regulation.
在 17 名患者中，慢性特发性恶心与直立不耐受（OI）相关，通过异常倾斜台试验（88%）或胃节律紊乱（71%）来确定。氟氢可的松治疗后，71%的患者恶心改善超过 26%，6%的患者改善 1-25%，24%的患者无改善。在 6 名受试者中，>50%恶心改善后重复进行 EGG，结果仍异常，这表明恶心与胃节律紊乱无关。
在这组恶心患者中，EGG 异常与 OI 的关联提示自主调节的全身性紊乱。
