Papakonstantinou E, Liapis A, Kairi-Vassilatou E, Iavazzo C, Kleanthis C K, Kondi-Pafiti A
Pathology Laboratory, Aretaieion University Hospital, Athens, Greece.
Eur J Gynaecol Oncol. 2011;32(3):331-3.
A case is reported of a 27-year-old pregnant woman with ovarian tumors, measuring 12 cm and 11.5 cm in the greatest diameter, discovered during investigation for virilization symptoms. Termination of the pregnancy at the 22nd week of gestation and tumorectomy with both adnexa were performed, with the provisional diagnosis of arrhenoblastoma. Pathological examination of the tumors showed typical Krukenberg neoplasms and subsequent upper GI tract endoscopy revealed a gastric cancer that was excised. The pathological examination revealed a diffuse type gastric adenocarcinoma with signet ring morphology, similar to ovarian tumors. In any case of ovarian tumor with unusual hormonal manifestations, in addition to hormonally active sex cord-stromal neoplasms, metastatic ovarian tumors must be considered as well, especially in cases of bilateral tumors.
报告了一例27岁的孕妇，在对男性化症状进行检查时发现卵巢肿瘤，最大直径分别为12厘米和11.5厘米。在妊娠第22周终止妊娠并进行了肿瘤切除及双侧附件切除术，初步诊断为男性细胞瘤。肿瘤的病理检查显示为典型的库肯勃瘤，随后的上消化道内镜检查发现了一例已切除的胃癌。病理检查显示为弥漫型胃腺癌，具有印戒形态，与卵巢肿瘤相似。在任何出现异常激素表现的卵巢肿瘤病例中，除了具有激素活性的性索间质肿瘤外，还必须考虑转移性卵巢肿瘤，尤其是双侧肿瘤的情况。
