Bonetti L Reggiani, Lupi M, Stauder E, Bergamini S, Scuri M, Maiorana A
Dipartimento Integrato Servizi Diagnostici e di Laboratorio e di Medicina Legale, Sezione di Anatomia Patologica. Universitá di Modena e Reggio Emilia, Italy.
Pathologica. 2011 Apr;103(2):40-2.
We report the case of a 70-year-old man with symptoms of urinary obstruction and haematuria, with histological diagnosis of primary signet-ring cell carcinoma of the prostate. Almost 90% of the tumour cells contained characteristic intracytoplasmic vacuoles that positively stained with diastase-digested PAS, Alcian blue and mucicarmine. The positive immunostaining for PSA and PSAP confirmed the prostatic origin of the tumour. Although the patient received hormonal therapy, the disease progressed and the patient died 11 months after surgery.
我们报告了一例70岁男性患者，其有尿路梗阻和血尿症状，组织学诊断为前列腺原发性印戒细胞癌。几乎90%的肿瘤细胞含有特征性的胞浆内空泡，这些空泡对淀粉酶消化后的PAS、阿尔辛蓝和黏液卡红呈阳性染色。PSA和PSAP的阳性免疫染色证实了肿瘤的前列腺起源。尽管患者接受了激素治疗，但疾病仍进展，患者术后11个月死亡。
