Nussinovitch Udi, Elishkevitz Keren Politi, Kaminer Keren, Nussinovitch Moshe, Segev Shlomo, Volovitz Benjamin, Nussinovitch Naomi
The Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel.
Pacing Clin Electrophysiol. 2011 Nov;34(11):1498-502. doi: 10.1111/j.1540-8159.2011.03178.x.
High values of resting heart rate were found to be correlated with adverse outcomes in various patient groups. Heart rate variability (HRV) is a reliable technique in determining autonomic nervous system function. Our aim was to evaluate whether a 10-second resting heart rate obtained from a resting electrocardiogram (ECG), could be used as a reliable evaluation of short-term HRV.
Seventy-nine healthy volunteers were included in the study. All participants underwent a 10-second ECG, and 5-minute HRV measurement under strict criteria.
A significantly negative correlation was found between resting heart rate and 5-minute max-RR, min-RR, standard deviation of normal RR intervals (SDNN), root mean square of successive differences of RR intervals (RMSSD), HRV triangular index, number of intervals differing by 50 milliseconds from the preceding interval (NN50), pNN50, standard deviation of the points perpendicular to the line of identity (SD1), standard deviation along the line of identity (SD2), and high frequency spectral component (HF). A significant positive correlation was found between resting heart rate and a 5-minute low frequency spectral component (LF) and LF/HF ratio. Specifically, max-RR and min-RR were found to have the best correlation with resting heart rate.
Resting heart rate obtained from a 10-second ECG can be used for crude estimation of all HRV results in healthy individuals who do not take medications, with variable efficacy depending on the measured parameter. Resting heart rate was especially efficient in predicting max-RR and min-RR. Further research should focus on assessing the reliability of a resting heart rate for HRV evaluation, in patients with autonomic dysfunction and high-risk cardiac patients.
在不同患者群体中，静息心率较高与不良预后相关。心率变异性（HRV）是确定自主神经系统功能的可靠技术。我们的目的是评估从静息心电图（ECG）获得的10秒静息心率是否可用于可靠评估短期HRV。
79名健康志愿者纳入本研究。所有参与者均接受10秒心电图检查，并在严格标准下进行5分钟HRV测量。
静息心率与5分钟最大RR间期、最小RR间期、正常RR间期标准差（SDNN）、RR间期连续差值的均方根（RMSSD）、HRV三角指数、与前一个间期相差50毫秒的间期数量（NN50）、pNN50、垂直于恒等线的点的标准差（SD1）、沿恒等线的标准差（SD2）以及高频谱成分（HF）之间存在显著负相关。静息心率与5分钟低频谱成分（LF）和LF/HF比值之间存在显著正相关。具体而言，最大RR间期和最小RR间期与静息心率的相关性最佳。
对于未服用药物的健康个体，从10秒心电图获得的静息心率可用于粗略估计所有HRV结果，根据测量参数的不同，其有效性各异。静息心率在预测最大RR间期和最小RR间期方面尤为有效。进一步的研究应聚焦于评估自主神经功能障碍患者和高危心脏病患者静息心率用于HRV评估的可靠性。
