Rutgers University, School of Environmental and Biological Sciences, Department of Plant Biology and Pathology, Cook Campus, New Brunswick, NJ 08901-8520, USA.
Fitoterapia. 2011 Oct;82(7):1062-74. doi: 10.1016/j.fitote.2011.07.003. Epub 2011 Jul 21.
Ethanolic extracts of diploid Artemisia dracunculus L. (wild tarragon) from populations in the U.S., and polyploid tarragon from a variety of sources, were screened for the anti-diabetic compounds davidigenin; sakuranetin; 2',4'-dihydroxy-4-methoxydihydrochalcone; 4,5-di-O-caffeoylquinic acid; 5-O-caffeoylquinic acid and 6-demethoxycapillarisin using LC-MS. Only decaploid plants contained all six target compounds and were the only plants that contained davidigenin and 2,4-dihydroxy-4-methoxydihydrochalcone. These results exhibit the importance of germplasm selection and provenance when studying plants for medicinal activity. Relying only on the "right species" for consistent medicinal activities may not be sufficient, as intraspecific variation may be highly significant.
采用 LC-MS 方法，对来自美国的二倍体龙蒿（野生龙蒿）和来自不同来源的多倍体龙蒿的乙醇提取物进行了抗糖尿病化合物大蓟苷元；樱花素；2',4'-二羟基-4-甲氧基二氢查耳酮；4,5-二-O-咖啡酰奎宁酸；5-O-咖啡酰奎宁酸和 6-去甲氧基毛蕊异黄酮的筛选。只有六倍体植物含有所有六种目标化合物，也是唯一含有大蓟苷元和 2,4-二羟基-4-甲氧基二氢查耳酮的植物。这些结果表明，在研究具有药用活性的植物时，种质选择和起源非常重要。仅依靠“正确的物种”来获得一致的药用活性可能还不够，因为种内变异可能非常显著。
