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Predisposition to the development of IL-9-secreting T cells in atopic infants.

作者信息

Yao Weiguo, Tepper Robert S, Kaplan Mark H

出版信息

J Allergy Clin Immunol. 2011 Dec;128(6):1357-1360.e5. doi: 10.1016/j.jaci.2011.06.019. Epub 2011 Jul 28.

DOI:10.1016/j.jaci.2011.06.019

PMID:21798577

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3208121/

Abstract

摘要

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Predisposition to the development of IL-9-secreting T cells in atopic infants.

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J Immunol. 2011 Mar 15;186(6):3283-8. doi: 10.4049/jimmunol.1003049.

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J Allergy Clin Immunol. 2010 Sep;126(3):483-8.e1. doi: 10.1016/j.jaci.2010.06.028.

The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation.

Nat Immunol. 2010 Jun;11(6):527-34. doi: 10.1038/ni.1867. Epub 2010 May 2.

IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells.

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Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset.

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J Allergy Clin Immunol. 2008 Oct;122(4):760-765. doi: 10.1016/j.jaci.2008.07.022. Epub 2008 Aug 28.

Allergen-induced interleukin-9 production in vitro: correlation with atopy in human adults and comparison with interleukin-5 and interleukin-13.

Clin Exp Allergy. 2006 Feb;36(2):174-82. doi: 10.1111/j.1365-2222.2006.02422.x.

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Predisposition to the development of IL-9-secreting T cells in atopic infants.

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