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追求阳光以增加皮肤维生素 D 合成:当预防信息相冲突时。

Sun-seeking behavior to increase cutaneous vitamin D synthesis: when prevention messages conflict.

机构信息

Comstock Center for Public Health Research and Prevention, Washington County, MD, USA.

出版信息

Public Health Rep. 2011 Jul-Aug;126(4):533-9. doi: 10.1177/003335491112600409.

DOI:10.1177/003335491112600409
PMID:21800747
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3115212/
Abstract

OBJECTIVES

The public has long been encouraged to engage in sun-safe practices to minimize exposure to sunlight, the major cause of nonmelanoma skin cancer. More recently, some have advocated unprotected sun exposure to increase cutaneous synthesis of vitamin D as a way to promote health. We assessed the net result of these conflicting messages.

METHODS

In a cross-sectional survey in 2007, questionnaires were mailed to participants of an ongoing cohort study in Washington County, Maryland. The study population consisted of 8,027 adults (55% response rate).

RESULTS

Thirty percent of respondents were aware that unprotected sun exposure increased endogenous vitamin D levels. Among those who were aware of this benefit, 42% reported going out into the sun to increase vitamin D levels. Sun-seeking to increase vitamin D production did not significantly differ according to self-reported personal history of skin cancer, but was significantly higher among women, older age groups, those with less education, and vitamin D supplement users.

CONCLUSION

A substantial proportion of respondents reported sun-seeking behavior expressly to increase endogenous vitamin D levels. The message about sun exposure and vitamin D is reaching the general public; however, this finding poses challenges to skin cancer prevention efforts.

摘要

目的

长期以来,公众一直被鼓励采取防晒措施,以尽量减少阳光暴露,这是导致非黑素瘤皮肤癌的主要原因。最近,一些人提倡不采取保护措施的阳光暴露,以增加皮肤中维生素 D 的合成,从而促进健康。我们评估了这些相互矛盾的信息的净结果。

方法

在 2007 年的一项横断面调查中,向马里兰州华盛顿县正在进行的队列研究的参与者邮寄了问卷。研究人群由 8027 名成年人组成(回应率为 55%)。

结果

30%的受访者知道无保护的阳光暴露会增加内源性维生素 D 水平。在那些意识到这一好处的人中,42%的人报告说为了增加维生素 D 水平而晒太阳。为了增加维生素 D 的产生而晒太阳的行为与自我报告的皮肤癌个人史没有显著差异,但在女性、年龄较大的人群、受教育程度较低的人群和维生素 D 补充剂使用者中明显更高。

结论

相当一部分受访者报告说,他们特意晒太阳是为了增加内源性维生素 D 水平。关于阳光暴露和维生素 D 的信息已经传达给了公众;然而,这一发现给皮肤癌预防工作带来了挑战。

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本文引用的文献

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Common genetic determinants of vitamin D insufficiency: a genome-wide association study.常见的维生素 D 不足遗传决定因素:全基因组关联研究。
Lancet. 2010 Jul 17;376(9736):180-8. doi: 10.1016/S0140-6736(10)60588-0. Epub 2010 Jun 10.
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Incidence estimate of nonmelanoma skin cancer in the United States, 2006.2006年美国非黑色素瘤皮肤癌的发病率估计
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Effects of ambient sunlight and photoprotection on vitamin D status.环境阳光和光保护措施对维生素 D 状况的影响。
Dermatol Ther. 2010 Jan-Feb;23(1):48-60. doi: 10.1111/j.1529-8019.2009.01290.x.
4
Recommended summer sunlight exposure levels can produce sufficient (> or =20 ng ml(-1)) but not the proposed optimal (> or =32 ng ml(-1)) 25(OH)D levels at UK latitudes.推荐的夏季阳光暴露水平可以产生足够的(≥20ng/ml)但不是建议的最佳(≥32ng/ml)25(OH)D 水平在英国纬度。
J Invest Dermatol. 2010 May;130(5):1411-8. doi: 10.1038/jid.2009.417. Epub 2010 Jan 14.
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Vitamin D in health and disease: an insight into traditional functions and new roles for the 'sunshine vitamin'.维生素 D 在健康和疾病中的作用:传统功能与“阳光维生素”新角色的深入了解。
Nutr Res Rev. 2009 Dec;22(2):118-36. doi: 10.1017/S0954422409990102.
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Changes in skin tanning attitudes. Fashion articles and advertisements in the early 20th century.皮肤晒黑观念的变化。20世纪初的时尚文章与广告。
Am J Public Health. 2009 Dec;99(12):2140-6. doi: 10.2105/AJPH.2008.144352. Epub 2009 Oct 21.
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Skin cancer prevention in Australia.澳大利亚皮肤癌预防。
Br J Dermatol. 2009 Nov;161 Suppl 3:116-23. doi: 10.1111/j.1365-2133.2009.09459.x.
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Vitamin D: bone and beyond, rationale and recommendations for supplementation.维生素D:骨骼及其他方面,补充的理论依据与建议
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