Department of Anesthesiology, ShaareZedek Medical Center, Jerusalem, Israel.
J Perinat Med. 2011 Nov;39(6):697-700. doi: 10.1515/jpm.2011.088. Epub 2011 Jul 29.
Epidural analgesia in older and multiparous women has been associated with risks. The aim of this study was to compare epidural analgesia use for labor/delivery in grand-grand multiparous women (GGMP; ≥10 births) relative to that in similar-aged women with lesser parity.
This was a prospective observational study of advanced age gravida. All laboring women in a six-month period admitted to a tertiary Israeli center were included if they were advanced age (≥36 years old) with one to two previous births (Low parity; n=128) or four to five previous births (Medium parity; n=181), and all GGMP (any age; n=187). Primary outcome was comparison of requests for and use of epidural analgesia for labor/delivery.
There were no significant differences across parity groups in percent of gravida requesting or receiving epidural analgesia (46.5-59.4%). Time from admission to epidural administration (range mean times: 168-187 min) and from advent of epidural to delivery (range mean times: 155-160 min) were comparable across parity groups. Use of other analgesia (5.8-8%) was not significantly different.
Requests for and use of epidural analgesia was comparable in older gravida and was not correlated with parity. Mean times from presentation to epidural administration, mean cervical dilatation at epidural initiation, and mean time from performing of epidural to delivery were comparable across groups.
硬膜外镇痛在高龄和多产妇中与风险相关。本研究的目的是比较高龄和多产妇(≥10 次分娩)与年龄相似、分娩次数较少的产妇在分娩时使用硬膜外镇痛的情况。
这是一项前瞻性观察性高龄产妇研究。在六个月期间,所有在以色列一家三级中心分娩的高龄产妇(≥36 岁,有一次或两次分娩史[低产次];n=128)或四次或五次分娩史(中产次;n=181),以及所有高龄和多产妇(任何年龄;n=187)均被纳入研究。主要结局是比较分娩时请求和使用硬膜外镇痛的情况。
在请求和接受硬膜外镇痛的产妇比例(46.5%-59.4%)方面,不同产次组之间无显著差异。从入院到硬膜外给药的时间(范围平均时间:168-187 分钟)和从硬膜外开始到分娩的时间(范围平均时间:155-160 分钟)在产次组之间相似。其他镇痛方法的使用(5.8%-8%)无显著差异。
高龄产妇对硬膜外镇痛的请求和使用情况相似,与产次无关。从就诊到硬膜外给药的平均时间、硬膜外起始时的宫颈扩张平均时间以及从硬膜外操作到分娩的平均时间在各组之间相似。