Department of Ophthalmology, Gachon University Gil Hospital, Incheon, Korea.
Acta Ophthalmol. 2012 Feb;90(1):e68-72. doi: 10.1111/j.1755-3768.2011.02208.x. Epub 2011 Jul 29.
To investigate the effect of change of body posture from supine to lateral decubitus position (LDP) on intraocular pressure (IOP) in healthy young subjects.
We evaluated 38 eyes of 19 healthy young Korean subjects. IOP was measured using Tonopen XL in both eyes in the sitting and supine position, 5 and 30 min after right LDP and 5 min after returning to the supine position. A week later, IOP was measured in the same sequence except that the subjects assumed the left LDP. The eye on the lower side in the LDP was termed as a dependent eye.
The mean IOP of the dependent eyes increased significantly at 5 min after changing from supine to right (16.26 ± 2.73 mmHg versus 18.54 ± 2.95 mmHg, p < 0.01) or left LDP (15.53 ± 2.41 mmHg versus 17.53 ± 3.37 mmHg, p < 0.01); this IOP increase in the dependent eyes persisted at 30 min after changing to right (18.47 ± 2.97 mmHg, p < 0.01) or left LDP (17.79 ± 2.20 mmHg, p < 0.01). Upon returning to the supine position, IOP of the dependent eyes decreased significantly (16.83 ± 2.67 mmHg, p < 0.01 for right LDP and 16.47 ± 2.32 mmHg, p < 0.01 for left). However, this effect of the positional change was not found in the non-dependent eyes (all, p > 0.05). Mean IOP in the dependent eye was significantly higher than that in the non-dependent eye at 30 min after changing to the right (+0.89 ± 1.52 mmHg) or left LDP (+1.84 ± 2.03 mmHg).
The postural change from supine to LDP significantly increased IOP of the dependent eyes.
研究从仰卧位变为侧卧位时(LDP)对健康年轻受试者眼内压(IOP)的影响。
我们评估了 19 名健康年轻韩国受试者的 38 只眼。使用 Tonopen XL 在坐位和仰卧位下分别测量双眼的 IOP,然后在右侧 LDP 后 5 分钟和 30 分钟以及返回仰卧位后 5 分钟测量 IOP。一周后,除了让受试者采用左侧 LDP 外,按照相同的顺序测量 IOP。在 LDP 中处于较低侧的眼睛被称为依赖眼。
依赖眼从仰卧位变为右侧(16.26 ± 2.73 mmHg 变为 18.54 ± 2.95 mmHg,p < 0.01)或左侧 LDP(15.53 ± 2.41 mmHg 变为 17.53 ± 3.37 mmHg,p < 0.01)时,IOP 显著升高;这种依赖眼的 IOP 升高在改为右侧(18.47 ± 2.97 mmHg,p < 0.01)或左侧 LDP(17.79 ± 2.20 mmHg,p < 0.01)30 分钟后仍持续存在。当回到仰卧位时,依赖眼的 IOP 显著降低(右侧 LDP 时为 16.83 ± 2.67 mmHg,p < 0.01;左侧时为 16.47 ± 2.32 mmHg,p < 0.01)。然而,这种位置变化的影响在非依赖眼并未发现(均,p > 0.05)。在改为右侧(+0.89 ± 1.52 mmHg)或左侧 LDP(+1.84 ± 2.03 mmHg)后 30 分钟,依赖眼的平均 IOP 明显高于非依赖眼。
从仰卧位变为 LDP 时,依赖眼的眼压显著升高。