Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Health Qual Life Outcomes. 2011 Jul 29;9:57. doi: 10.1186/1477-7525-9-57.
Burning mouth syndrome is a chronic disorder that is characterized by a burning sensation and a normal clinical appearance of the oral mucosa. This condition often affects the health-related quality of life in patients. As such, the aim of this study was to compare the health-related quality of life of patients with BMS and healthy controls, using the validated Portuguese versions of the SF-36 and OHIP-49 questionnaires.
A calculated sample of Brazilian patients with BMS (n = 26) was compared with a control group (n = 27), paired for gender and age. Sociodemographic information and clinical characteristics were obtained, and interviews were conducted using the SF-36 and OHIP-49. To evaluate the normality of the variables, we used the Kolmogorov-Smirnov test. The chi-square test, Fisher exact test and Mann-Whitney U-Test were used to compare sociodemographic and clinical characteristics of individuals with BMS and controls Mann-Whitney U-test were carried out to compare SF-36 and OHIP-49 between BMS patients and controls. The significance level was set at 0.05. To compare the dimensions of the SF-36 and OHIP-49 between BMS patients and controls, we considered Bonferroni correction. So for comparison of the dimensions, the significance level was set at 0.00625 for SF-36 and at 0.00714 for OHIP-49.
The clinical and demographic data were similar in both groups (P > 0.05). SF-36 scores were significantly lower in all domains for patients with BMS (P < 0.00625). OHIP-49 scores were higher for individuals with BMS (P < 0.00714).
BMS has a negative impact on the health-related quality of life of individuals, as can be shown by instruments such as the SF-36 and OHIP-49. So, the evaluation of quality of life might be useful for more information about the nature and severity of BMS, to evaluate the effects of treatment protocols, in order to improve their outcomes by means a humanized clinical practice.
灼口综合征是一种以口腔黏膜正常的烧灼感和临床症状为特征的慢性疾病。这种情况常影响患者的健康相关生活质量。因此，本研究旨在使用经过验证的 SF-36 和 OHIP-49 问卷比较 BMS 患者和健康对照组的健康相关生活质量。
对巴西 BMS 患者（n=26）的样本进行计算，并与对照组（n=27）进行比较，按性别和年龄配对。收集社会人口统计学信息和临床特征，并使用 SF-36 和 OHIP-49 进行访谈。为了评估变量的正态性，我们使用了 Kolmogorov-Smirnov 检验。使用卡方检验、Fisher 精确检验和 Mann-Whitney U 检验比较 BMS 患者和对照组的社会人口统计学和临床特征。Mann-Whitney U 检验用于比较 BMS 患者和对照组之间的 SF-36 和 OHIP-49。显著性水平设为 0.05。为了比较 BMS 患者和对照组之间 SF-36 和 OHIP-49 的维度，我们考虑了 Bonferroni 校正。因此，对于维度的比较，SF-36 的显著性水平设定为 0.00625，OHIP-49 的显著性水平设定为 0.00714。
两组的临床和人口统计学数据相似（P>0.05）。BMS 患者的 SF-36 所有维度的评分均显著较低（P<0.00625）。BMS 患者的 OHIP-49 评分较高（P<0.00714）。
BMS 对个体的健康相关生活质量有负面影响，这可以通过 SF-36 和 OHIP-49 等工具来显示。因此，生活质量评估可能有助于更全面地了解 BMS 的性质和严重程度，评估治疗方案的效果，通过人性化的临床实践来改善其结果。
