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一项关于舌保护器治疗灼口综合征疗效的前瞻性、随机研究。

A prospective, randomized study on the efficacy of tongue protector in patients with burning mouth syndrome.

机构信息

Department of Oral Medicine, University of Murcia, Murcia, Spain.

出版信息

Oral Dis. 2011 Apr;17(3):277-82. doi: 10.1111/j.1601-0825.2010.01737.x. Epub 2010 Sep 23.

Abstract

OBJECTIVE

To apply a tongue protector with habit-modifying therapy through self-control, in the patients with burning mouth syndrome (BMS).

METHODS

A prospective, randomized study was made of 65 consecutive patients with BMS. Fifty subjects were randomized to two groups: group A (informed) and group B (informed and the application of a tongue protector). The symptoms were evaluated by VAS, whereas the psychological profile was assessed using the HAD, with application of the quality of life questionnaires SF-36 and OHIP-49. The duration of treatment was 2 months.

RESULTS

Fifty patients (46 females and 4 males) completed the study. The VAS scores in group B were 8.2 at baseline and 4.5 after 2 months. The respective scores in group A were 7.1 and 5.6 - the differences between the two groups being significant (P < 0.001). In group B the OHIP-49 yielded lower scores for most of the scales, with significant differences vs group A. In group B the SF 36 yielded significant differences vs group A in physical role, bodily pain, general health and emotional role.

CONCLUSIONS

Parafunctional traumatism of the tongue should be taken into account in the pathogenesis of BMS with a view to exploring new therapeutic options.

摘要

目的

通过自我控制,应用具有习惯修正疗法的舌保护器,治疗灼口综合征(BMS)患者。

方法

对 65 例连续 BMS 患者进行前瞻性、随机研究。50 名患者被随机分为两组:A 组(知情)和 B 组(知情并应用舌保护器)。采用视觉模拟评分(VAS)评估症状,采用 HADS 评估心理状况,并应用 SF-36 和 OHIP-49 生活质量问卷进行评估。治疗持续 2 个月。

结果

50 名患者(46 名女性和 4 名男性)完成了研究。B 组的 VAS 评分在基线时为 8.2,在 2 个月后为 4.5。A 组的相应评分分别为 7.1 和 5.6,两组之间的差异具有统计学意义(P<0.001)。B 组的 OHIP-49 在大多数量表中得分较低,与 A 组相比差异具有统计学意义。B 组的 SF-36 在生理角色、躯体疼痛、总体健康和情绪角色方面与 A 组相比差异具有统计学意义。

结论

应考虑舌的副功能创伤在 BMS 的发病机制中,以探索新的治疗选择。

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