Grand Rapids Medical Education Partners/Michigan State University Emergency Medicine Residency, 100 Michigan NE, MC 49, Grand Rapids, MI 49403, USA.
Neurol Clin. 2011 Aug;29(3):565-80. doi: 10.1016/j.ncl.2011.05.003. Epub 2011 Jun 24.
Antidepressants are the most commonly prescribed class of medications in the United States. The clinician should be mindful of the many antidepressants that can produce seizures following an accidental exposure or an overdose. A broader understanding of the seizure potential of antidepressants, combined with the ability to recognize individuals at risk for a seizure after an overdose, can aid clinicians in determining the need for inpatient monitoring, and help facilitate their treatment decisions.
抗抑郁药是美国最常用的处方药物类别。临床医生应注意许多抗抑郁药在意外暴露或过量服用后会引起癫痫发作。更广泛地了解抗抑郁药的致痫潜力,加上在过量服用后识别有癫痫发作风险的个体的能力,有助于临床医生确定是否需要住院监测,并帮助他们做出治疗决策。