School of Pharmacy, Chouksey Engineering College, Bilaspur, Chattishgarh, India.
Asian Pac J Trop Med. 2011 Jul;4(7):581-6. doi: 10.1016/S1995-7645(11)60150-8.
Filariasis is result of parasitic infection caused by three specific kinds of round worm. Lymphatic filariasis is found in under developed region of South America, Central Africa, pacific and Caribbian. It has been found for centuries, with main symptoms as elephant like swelling of the arms, legs and genitals. It is estimate that 120 millions peoples in the world have lymphatic filariasis. The spread of diseases and the challenge encountered in its management are discussed along with a review on drugs against filariasis in this article. Detail on clinical effect of drugs on the infection, safety profile, status in clinical practices and drug resistances are also covered.
丝虫病是由三种特定的圆线虫引起的寄生虫感染。淋巴丝虫病见于南美洲、中非、太平洋和加勒比地区的欠发达地区。它已经存在了几个世纪，主要症状是手臂、腿部和生殖器的象皮肿。据估计，全世界有 1.2 亿人患有淋巴丝虫病。本文讨论了疾病的传播和管理中遇到的挑战，以及抗丝虫病药物的研究进展。还详细介绍了药物对感染的临床效果、安全性概况、临床实践中的地位和耐药性。
