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[采用世界卫生组织新建议估计代谢综合征患病率。HERMEX研究]

[Prevalence of metabolic syndrome estimated with the new World Health Organization recommendations. The HERMEX study].

作者信息

Fernández-Bergés Daniel, Félix-Redondo Francisco J, Lozano Luis, Pérez-Castán José F, Sanz Héctor, Cabrera De León Antonio, Hidalgo Ana B, Morcillo Yolanda, Tejero Verónica, Alvarez-Palacios Paula

机构信息

Unidad de Investigación Don Benito-Villanueva, Programa de Investigación en Enfermedades cardiovasculares, Fundesalud, Gerencia SES Área sanitaria Don Benito-Villanueva, Badajoz, España.

出版信息

Gac Sanit. 2011 Nov-Dec;25(6):519-24. doi: 10.1016/j.gaceta.2011.05.009. Epub 2011 Jul 30.

Abstract

OBJECTIVES

The unification of criteria for the diagnosis of metabolic syndrome, together with the subsequent World Health Organization (WHO) proposal to eliminate diabetes and cardiovascular diseases from the diagnostic criteria, will change estimates of the known prevalence of this syndrome. The aim of this study was to determine the prevalence of metabolic syndrome in a health area of Badajoz (Spain) using the latest consensus criteria and eliminating diabetes and cardiovascular disease.

METHODS

We performed a cross-sectional population-wide study of randomly selected individuals aged between 25 and 79 years old in a health area of Badajoz. In all patients, data on their history of cardiovascular risk factors were gathered, waist circumference and blood pressure were measured and a fasting blood sample was collected. The prevalence of metabolic syndrome, following recent criteria, was compared by age and gender.

RESULTS

We recruited 2,833 individuals (46.5% men). The mean age was 51.2 years The prevalence of metabolic syndrome was 33.6% and was significantly higher in men (36.7% vs 30.9%; p < 0.001). The prevalence of metabolic syndrome fell significantly after exclusion of patients with diabetes or cardiovascular disease (20.8%; p < 0.001). The difference in prevalence between the distinct criteria was significant for the whole population and by sex (p < 0.000). A significant difference in prevalence between genders was observed from the age of 45-54 years in men and 55-64 years in women

CONCLUSIONS

The prevalence of metabolic syndrome in a health area of Badajoz is among the highest reported in population-based studies in Spain. Although estimates of the prevalence are decreased by the new international recommendations, a considerable proportion of the young population requires preventive measures.

摘要

目的

代谢综合征诊断标准的统一,以及世界卫生组织(WHO)随后提出的从诊断标准中剔除糖尿病和心血管疾病的提议,将改变该综合征已知患病率的估计值。本研究的目的是使用最新的共识标准并剔除糖尿病和心血管疾病,来确定西班牙巴达霍斯一个健康区域内代谢综合征的患病率。

方法

我们在巴达霍斯的一个健康区域对年龄在25至79岁之间随机选取的个体进行了一项全人群横断面研究。收集了所有患者的心血管危险因素病史数据,测量了腰围和血压,并采集了空腹血样。根据最新标准,按年龄和性别比较代谢综合征的患病率。

结果

我们招募了2833名个体(46.5%为男性)。平均年龄为51.2岁。代谢综合征的患病率为33.6%,男性患病率显著更高(36.7%对30.9%;p<0.001)。排除糖尿病或心血管疾病患者后,代谢综合征的患病率显著下降(20.8%;p<0.001)。不同标准之间的患病率差异在整个人群和按性别分组中均具有显著性(p<0.000)。在45 - 54岁的男性和55 - 64岁的女性中观察到性别之间患病率存在显著差异。

结论

巴达霍斯一个健康区域内代谢综合征的患病率在西班牙基于人群的研究中报告的患病率中处于较高水平。尽管新的国际建议降低了患病率的估计值,但相当一部分年轻人群仍需要采取预防措施。

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