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Effects of N-acyl homoserine lactone analogues on Porphyromonas gingivalis biofilm formation.N-酰基高丝氨酸内酯类似物对牙龈卟啉单胞菌生物膜形成的影响。
J Periodontal Res. 2010 Apr;45(2):255-61. doi: 10.1111/j.1600-0765.2009.01228.x. Epub 2009 Sep 23.
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Distinct roles of long/short fimbriae and gingipains in homotypic biofilm development by Porphyromonas gingivalis.牙龈卟啉单胞菌长/短菌毛和牙龈蛋白酶在同型生物膜形成中的不同作用
BMC Microbiol. 2009 May 26;9:105. doi: 10.1186/1471-2180-9-105.
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Comparative transcriptomic analysis of Porphyromonas gingivalis biofilm and planktonic cells.牙龈卟啉单胞菌生物膜与浮游细胞的比较转录组分析
BMC Microbiol. 2009 Jan 29;9:18. doi: 10.1186/1471-2180-9-18.
4
Determination of the genome sequence of Porphyromonas gingivalis strain ATCC 33277 and genomic comparison with strain W83 revealed extensive genome rearrangements in P. gingivalis.牙龈卟啉单胞菌菌株ATCC 33277的基因组序列测定以及与W83菌株的基因组比较显示,牙龈卟啉单胞菌存在广泛的基因组重排。
DNA Res. 2008 Aug;15(4):215-25. doi: 10.1093/dnares/dsn013. Epub 2008 Jun 3.
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A genome-wide approach to identify the genes involved in biofilm formation in E. coli.一种全基因组方法,用于鉴定大肠杆菌中参与生物膜形成的基因。
DNA Res. 2007 Dec 31;14(6):237-46. doi: 10.1093/dnares/dsm024. Epub 2008 Jan 7.
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Role of the Clp system in stress tolerance, biofilm formation, and intracellular invasion in Porphyromonas gingivalis.Clp系统在牙龈卟啉单胞菌的应激耐受性、生物膜形成及细胞内侵袭中的作用
J Bacteriol. 2008 Feb;190(4):1436-46. doi: 10.1128/JB.01632-07. Epub 2007 Dec 7.
7
Porphyromonas gingivalis minor fimbriae are required for cell-cell interactions.牙龈卟啉单胞菌的微小菌毛是细胞间相互作用所必需的。
Infect Immun. 2006 Oct;74(10):6011-5. doi: 10.1128/IAI.00797-06.
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Techniques for the growth of Porphyromonas gingivalis biofilms.牙龈卟啉单胞菌生物膜的生长技术
Periodontol 2000. 2006;42:27-35. doi: 10.1111/j.1600-0757.2006.00183.x.
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Identification and localization of extraradicular biofilm-forming bacteria associated with refractory endodontic pathogens.与难治性牙髓病病原体相关的根外生物膜形成细菌的鉴定与定位
Appl Environ Microbiol. 2005 Dec;71(12):8738-43. doi: 10.1128/AEM.71.12.8738-8743.2005.
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Localization of Porphyromonas gingivalis-carrying fimbriae in situ in human periodontal pockets.牙龈卟啉单胞菌携带菌毛在人类牙周袋中的原位定位
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牙龈卟啉单胞菌 ATCC 33277 生物膜形成过程中基因表达的时间进程。

Time course of gene expression during Porphyromonas gingivalis strain ATCC 33277 biofilm formation.

机构信息

Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan.

出版信息

Appl Environ Microbiol. 2011 Sep;77(18):6733-6. doi: 10.1128/AEM.00746-11. Epub 2011 Jul 29.

DOI:10.1128/AEM.00746-11
PMID:21803908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3187161/
Abstract

Chronological gene expression patterns of biofilm-forming cells are important to understand bioactivity and pathogenicity of biofilms. For Porphyromonas gingivalis ATCC 33277 biofilm formation, the number of genes differentially regulated by more than 1.5-fold was highest during the growth stage (312/2,090 genes), and some pathogen-associated genes were time-dependently controlled.

摘要

生物膜形成细胞的时间基因表达模式对于理解生物膜的生物活性和致病性非常重要。对于牙龈卟啉单胞菌 ATCC 33277 生物膜的形成,在生长阶段(312/2090 个基因),有超过 1.5 倍差异调控的基因数量最高,一些与病原体相关的基因是时间依赖性控制的。