植物科学与人类营养：评估植物化学素促进健康特性的挑战。
Plant science and human nutrition: challenges in assessing health-promoting properties of phytochemicals.
机构信息
Institute of Food Research, Norwich Research Park, Norwich NR47UA, United Kingdom.
出版信息
Plant Cell. 2011 Jul;23(7):2483-97. doi: 10.1105/tpc.111.087916. Epub 2011 Jul 29.
Abstract
The rise in noncommunicable chronic diseases associated with changing diet and lifestyles throughout the world is a major challenge for society. It is possible that certain dietary components within plants have roles both in reducing the incidence and progression of these diseases. We critically review the types of evidence used to support the health promoting activities of certain phytochemicals and plant-based foods and summarize the major contributions but also the limitations of epidemiological and observational studies and research with the use of cell and animal models. We stress the need for human intervention studies to provide high-quality evidence for health benefits of dietary components derived from plants.
摘要
随着世界各地饮食和生活方式的改变，与非传染性慢性疾病相关的问题日益严重，这对社会来说是一个重大挑战。某些植物性食物中的成分可能在降低这些疾病的发病率和进展方面发挥作用。我们批判性地回顾了用于支持某些植物化学物质和植物性食物促进健康的活动的证据类型，并总结了流行病学和观察性研究以及使用细胞和动物模型的主要贡献和局限性。我们强调需要进行人体干预研究，为源自植物的饮食成分对健康的益处提供高质量的证据。
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