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曲线、环形、圆盘、球体、穹顶和环形源的 TG-43 几何函数的数学解,以及质量保证的应用。

Mathematical solutions of the TG-43 geometry function for curved line, ring, disk, sphere, dome and annulus sources, and applications for quality assurance.

机构信息

Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.

出版信息

Phys Med Biol. 2011 Aug 21;56(16):5429-44. doi: 10.1088/0031-9155/56/16/022. Epub 2011 Jul 29.

Abstract

Analytic solutions for the TG-43 geometry function for curved line, ring, disk, sphere, dome and annulus shapes containing uniform distributions of air-kerma are derived. These geometry functions describe how dose distributions vary strictly due to source geometry and not including attenuation or scatter effects. This work extends the use of geometry functions for individual sources to applicators containing multiple sources. Such geometry functions may be used to verify dose distributions computed using advanced techniques, including QA of model-based dose calculation algorithms. The impact of source curvature on linear and planar implants is considered along with the specific clinical case of brachytherapy eye plaques. For eye plaques, the geometry function for a domed distribution is used with published Monte Carlo dose distributions to determine a radial dose function and anisotropy function which includes all the scatter and attenuation effects due to the phantom, eye plaque and sources. This TG-43 model of brachytherapy eye plaques exactly reproduces azimuthally averaged Monte Carlo calculations, both inside and outside the eye.

摘要

针对含有空气比释动能均匀分布的曲线、环形、圆盘、球体、穹顶和环形形状,推导出了 TG-43 几何函数的解析解。这些几何函数描述了剂量分布如何由于源几何形状而严格变化,而不包括衰减或散射效应。这项工作将单个源的几何函数的应用扩展到包含多个源的施源器。此类几何函数可用于验证使用先进技术计算的剂量分布,包括对基于模型的剂量计算算法的 QA。还考虑了源曲率对线性和平面植入物的影响,以及近距离治疗眼贴的具体临床案例。对于眼贴,使用发布的蒙特卡罗剂量分布为穹顶分布的几何函数确定径向剂量函数和各向异性函数,该函数包括由于体模、眼贴和源引起的所有散射和衰减效应。这种近距离治疗眼贴的 TG-43 模型完全再现了蒙特卡罗计算的方位平均,包括在眼内和眼外。

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