Granero Domingo, Pérez-Calatayud José, Ballester Facundo
Department of Atomic, Molecular and Nuclear Physics and IFIC, University of Valencia-CSIC, Burjassot, Spain.
Radiother Oncol. 2005 Jul;76(1):79-85. doi: 10.1016/j.radonc.2005.06.016.
High dose rate (HDR) brachytherapy is a highly extended practice in clinical brachytherapy today. Quality dose rate distribution datasets of the HDR sources used in a clinical treatment are required. Because of the different source designs, a specific dosimetry dataset is required for each source model. In the recently published BRAPHYQS-ESTRO Report, an overview of available dosimetric data for all HDR Ir-192 sources is given, pointing out the lack of data for one of the sources that is used by the BEBIG MultiSource afterloading system (BEBIG GmbH, Germany). The purpose of this study is to obtain detailed dose rate distributions in liquid water media around this source.
The Monte Carlo code GEANT4 was used to estimate dose rate in water and air-kerma strength around the Ir-192 source. All the details of the stainless steel encapsulated BEBIG HDR 1.1mm in external diameter has been included in the simulation.
A complete dosimetric dataset for the BEBIG Ir-192 HDR source is presented. TG43 dosimetric functions and parameters have been obtained as well as a 2D rectangular dose rate table, consistent with the TG43 dose calculation formalism. The dosimetric parameters and functions obtained for the BEBIG HDR source have been compared with that obtained in the literature for others HDR sources, showing that the use of specific datasets for this new source is justified.
This dataset can be used as input in the TPS and to validate its calculations. As policy of BRAPHYQS-ESTRO task group, this dataset will be incorporated to the website: available to users in excel format.
高剂量率(HDR)近距离放射治疗是当今临床近距离放射治疗中广泛应用的一种治疗方式。临床治疗中使用的HDR源需要高质量的剂量率分布数据集。由于源设计的不同,每个源模型都需要特定的剂量测定数据集。在最近发表的BRAPHYQS-ESTRO报告中,给出了所有HDR铱-192源可用剂量测定数据的概述,指出BEBIG多源后装系统(德国BEBIG GmbH公司)使用的其中一种源缺乏数据。本研究的目的是获得该源周围液态水介质中的详细剂量率分布。
使用蒙特卡罗代码GEANT4来估计铱-192源周围水中的剂量率和空气比释动能强度。模拟中包含了外径为1.1mm的不锈钢封装BEBIG HDR的所有细节。
给出了BEBIG铱-192 HDR源完整的剂量测定数据集。获得了TG43剂量测定函数和参数以及二维矩形剂量率表,与TG43剂量计算形式一致。将BEBIG HDR源获得的剂量测定参数和函数与文献中其他HDR源获得的进行了比较,表明为这种新源使用特定数据集是合理的。
该数据集可作为治疗计划系统(TPS)的输入并验证其计算。作为BRAPHYQS-ESTRO任务组的政策,该数据集将被纳入网站:以Excel格式供用户使用。